Array Biopharma Inc.

Ventirx Pharmaceuticals, Inc.

James Jeffry Howbert

Laurence Edward Burgess

Robert Hershberg

Gregory Dietsch

Joseph P Lyssikatos

Brad Newhouse

George A Doherty

Robert D Groneberg

Hong Woon Yang

Charles Todd Eary

Hong-Woon Yang

Zachary Jones

C Todd Eary

Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, fibrotic disease, cardiovascular disease, infectious disease, inflammatory disorder, graft rejection, or graft-versus-host disease.

Substituted benzoazepines as toll-like receptor modulators

Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-versus-host disease.

Provided are compositions and methods useful for modulation of signaling through the Toll-like receptors TLR7 and/or TLR8. The compositions and methods have use in treating or preventing disease, including cancer, autoimmune disease, infectious disease, inflammatory disorder, graft rejection, and graft-verses-host disease.

Growing community of inventors

Redmond, WA, United States of America

James Jeffry Howbert