International Business Machines Corporation

Other

James Jeffrey Wynne

Jerome Marvin Felsenstein

Barry Dean Goodman

Hershall William Kaufman

Jason Matthew Jacobs

James L Hedrick

Donna S Zupanski-Nielsen

Stephen Henry Gomory

Dimitri Kanevsky

Lior Horesh

Raya Horesh

Aleksandr Y Aravkin

Robert Stephen Olyha, Jr

Rangaswamy Srinivasan

Samuel E Blum

Jeffrey Scott Braun

John Francis Reintjes, Jr

A method for laser assisted delivery of therapeutic agents includes selectively controlling a valve connected to a first channel disposed within a first sidewall of a nozzle, applying, through the first channel, a first substance to penetrate dermis to a predetermined depth, and administering, through a second channel unconnected with the valve and disposed within a second sidewall of the nozzle, a second substance to remove debris.

Laser-assisted transdermal delivery of nanoparticulates and hydrogels

A method for controlled ablation of target tissue includes activating laser ablation of hyperkeratotic tissue upon detecting a trigger input signal, detecting a photo-acoustical signature due to the laser ablation of the hyperkeratotic tissue, detecting a change in the photo-acoustical signature due to the laser ablation of a material different than the hyperkeratotic tissue, and ceasing the laser ablation upon detecting, by a signal processor, the change in the photo-acoustical signature.

Laser-assisted treatment of Pachyonychia Congenita

A laser treatment system includes a laser device configured to produce a laser beam at a wavelength in an ultraviolet spectrum to provide for tissue ablation, a lens configured to focus and direct the laser beam to a site to form an opening in a surface of the site, a valve connected to a first channel, and a nozzle that emits the laser beam and controls delivery of at least a first substance and a second substance to the site. A portion of the first channel is disposed within a first sidewall of the nozzle to deliver the first substance, and a second channel unconnected with the valve is disposed within a second sidewall of the nozzle to deliver the second substance.

Systems for laser assisted delivery of therapeutic agents include an ultraviolet laser configured to produce a laser beam at a wavelength appropriate for tissue ablation; a lens configured to focus and direct the laser beam to a site, such that an opening is produced in a surface of the site's tissue; a nozzle having an aperture that emits the laser beam and that controls delivery of one or more agents to the site; and an imaging device configured to monitor a depth of penetration of the one or more agents into the site's tissue.

Methods and systems for laser assisted delivery of therapeutic agents include preparing a site with an ultraviolet laser beam, at a wavelength appropriate for tissue ablation, such that an opening is produced in a surface of the site's tissue; and applying one or more agents to the prepared site, such that the agents penetrate the tissue through the opening to a predetermined depth.

A sensory hologram system includes a holographic system generating a holographic image, a sensory imparting system augmenting the holographic image, a detector configured to detect a location of a target, and a processor synchronizing the holographic system and the sensory imparting system based on the location of the target.

Sensory holograms

The present invention is an apparatus to provide a virtual tennis net that can be placed on any convenient surface having two movable poles each having a light source dependent thereon; at least two scanning mirrors; at least two retroflectors; at least two beam splitters; at least two photo-detectors; and an audible or visible signal device that is actuated in response to interruptions of light falling on said photo-detectors such that when a the light beam is interrupted by a tennis ball, the beam is momentarily blocked and the signal to the photo-detector is interrupted, providing a signal that is used to trigger a light or sound signal that indicates the ball did not pass over the virtual net.

Off court tennis

A laser system (called a UV Dermablator) and method that enables a clean, precise removal of skin while minimizing collateral damage to the skin underlying the treated region. The depth of ablation can be controlled via feedback from the physiology of the skin, namely the infusion of blood into the area of excision when skin has been ablated to a sufficient depth to produce bleeding. A second laser, such as a uv light source with a different wavelength, to penetrate the blood, heating it sufficiently to coagulate the blood. Other features provide precise control, permitting the epidermis to be removed down to the papillary dermis, following the undulations of the papillary dermis. This lateral and depth control may be accomplished by using careful observation, assisted by spectroscopic detection, to identify when the epidermis has been removed, exposing the underlying dermis, with spatial resolution appropriate for the spacing of the undulations of the papillary dermis. Yet other features which provide a feedback control mechanism which utilizes the optical characteristics such as the color, appearance and remittance of the definable skin layers to control the depth of ablation at each location.

Laser dermablator and dermablation

An improved dental procedure and apparatus where ultraviolet radiation pulses are used to etch selectively both hard tissue and soft tissue in dental procedures. There exists distinct ablation thresholds for hard and soft tissue which are dependent on the material being ablated for a given wavelength of the ultraviolet radiation. Sufficient differences in ablation threshold exist for enamel, dentin, and carious material, thereby allowing dentists to perform both hard tissue and soft tissue procedures without excess damage to healthy enamel, dentin or other pulp structures.

Dental procedures and apparatus using ultraviolet radiation

An improved dental procedure contacts a tooth with a fluoride carrier to produce a fluoride containing layer on the tooth. The tooth is then irradiated with UV radiation in the wavelength range of 100-400 nm. The fluoride carrier is at least 70% transparent to UV radiation, and the radiation is provided with sufficiently low energy to avoid inflicting pain on the patient.

An improved dental procedure and apparatus where ultraviolet radiation pulses are used to etch selectively both hard tissue and soft tissue in dental procedures. There exists distinct ablation thresholds for hard and soft tissue which are dependent on the material being ablated for a given wavelength of the ultraviolet radiation. Sufficient differences in ablation threshold exist for enamel, dentin, and carious material, thereby allowing dentists to perform both hard tissue and soft tissue procedures without excess damage of healthy enamel, dentin or other pulp structures.

Growing community of inventors

Mount Kisco, NY, United States of America

James Jeffrey Wynne