Conformal Medical, Inc.

Omnisonics Medical Technologies, Inc.

Gi Dynamics, Inc.

Morphic Medical, Inc.

James H Loper

Andy H Levine

David A Melanson

Aaron V Kaplan

Carol A Devellian

Ronald B Lamport

Michael T Radford

Peter J Shank

Bradley A Hare

Andres Chamorro, Iii

Barry Maxwell

Ian K Parker

Ryan Hanlon

Sean K Holmes

Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. Severing the tether and proximally retracting a control on the hand piece by a distance causes the severed end to advance distally by at least about twice that distance. A loader includes a conical portion with guides and a reservoir for submerging the foam prior to loading and delivery.

Devices and methods for excluding the left atrial appendage

Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body carried by the frame. The device may have a thromboresistant cover at a proximal end and a thromboresistant coating on the foam body. The frame may have recapture struts inclining radially outwardly in the distal direction from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame to engage tissue. The anchors can also be reversible to allow retraction of the anchors and repositioning or retrieval of the device.

Devices and methods are described for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow to prevent blood from clotting within the LAA and subsequently embolizing, particularly in patients with atrial fibrillation. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame and an expandable and conformable tubular foam body. The device may have a thromboresistant cover at a proximal end. The frame may have recapture struts inclining radially outwardly from a central hub. The frame may have axially extending side wall struts, with adjacent pairs of side wall struts joined at one or more apexes. Anchors extend from the frame and into the foam to engage tissue.

Systems, devices and methods for occluding the left atrial appendage (LAA). The device excludes the LAA from blood flow. The implantable device is delivered via transcatheter delivery into the LAA and secured within the LAA. The implant comprises an expandable and compliant frame having anchors and an expandable and conformable tubular foam body. A delivery and tether retraction system includes a handle for controlling a pusher and tether. The pusher may be moved a distance away from the implant without changing the orientation of the implant, while the tether is still attached to the implant. A loader includes a conical portion with guides and a reservoir for submerging the foam implant prior to loading and delivery.

A delivery system for placing a gastrointestinal device in a mammalian gastrointestinal tract comprises a container assembly; a gastrointestinal implant device that includes proximal and distal ends stored within the container assembly, the proximal end including an anchor and the distal end including a sleeve, coupled to the anchor and folded into the container assembly; and an inner extension to draw a portion of the sleeve from the anchor and from the container assembly as the anchor is retained therein. The inner extension comprises an atraumatic tip, such as a ball, that includes a guidewire rail. Further, a handle is provided that retains or captures an inner catheter within the handle. Within the handle is an elongated element that surrounds a portion of the catheter. A button on a side of the handle is configured to cause engagement of the catheter via the element when the button is depressed.

Devices and methods for placing a gastrointestinal device

An implant () includes a protrusion () with an open or rounded loop () (or open head) connected to a collapsible anchor. The protrusion may include a straight length of wire () or a helical length wire, with one or more wire loops () at the end of the length forming the loop. Upon deployment within the gastrointestinal tract, the protrusion expands from a collapsed state, alongside the anchor, to a relaxed state, in which the protrusion extends outward from the anchor. As the protrusion expands to its relaxed state, it pushes the loop into the wall of the duodenum, causing the loop to penetrate the duodenal wall. A pocket of scar tissue forms about the head and possibly through an opening in the head, securing the anchor within the duodenum. The implant may also include a thin-walled sleeve that is coupled to the anchor and extended from the anchor into the intestine.

Anchors with open heads

The present invention provides an apparatus and method for a torque limiting wrench used for applying a torque to a medical device to prevent damage to the medical device by providing a predetermined torque limit to indicate when the predetermined torque is reached. The torque limiting wrench comprises a gripping mechanism for engaging a medical device, a handle extending from the gripping mechanism and a torque limiting assembly contained within a length of the handle. A predetermined torque is set by the torque limiting assembly to provide an indicator to prevent damage to the acoustic characteristics of the medical device. The torque limiting wrench comprises a material that can undergo a sterilization process.

Torque limiting wrench for an ultrasonic medical device

The invention is directed to a container for storage, dispensation, transport and disposal of a medical device such a disposable ultrasonic surgical probe, that allows its dispensation for use, and for its safe storage and disposal after use, thereby protecting the user from the hazards of needle pricks and possible contamination from small-diameter probes. The container of the present invention also provides a mechanism for restricting access to the probe to prevent its reuse, and a method for its safe attachment to and detachment from an ultrasonic medical device. The container comprises a cylindrical tube having two ends and an inner surface defining a space for containing the probe. The probe is held within the cylindrical section of the container by a locking means that allows a single dispensation for its use and enables its disposal after use in an inaccessible manner, so as to enable its attachment and detachment to the non-disposable segment of the device such as an ultrasonic probe handle without requiring direct handling by the user. The user, is therefore protected from against accidental sticks from a possibly contaminated probe. The container also prevents re-use of the probe, and provides a means for its safe disposal.

Growing community of inventors

Wales, MA, United States of America

James H Loper