Baxter Travenol Laboratories, Inc.

James H DeVries

Herbert M Cullis

Michael B Uffer

David A Lohr

Rodolfo R Rodriquez

The monitor and fluid circuit assembly is used with a blood processing apparatus which is adapted for separating platelets from whole blood. The assembly is easily and simply attached to the apparatus and includes a holder, a plurality of flexible tubings held in and extending through the holder, monitor devices fixed within the holder and series coupled to various ones of the tubings and at least one tubing having a transparent wall section which is positioned adjacent an optical sensor of the apparatus. Several tubings extend in loops from the holder and are adapted for being received over and forming part of peristaltic pumps of the apparatus so that fluid can be pumped through the tubings. Other portions of some of the tubings extending from the holder are held in an umbilicus which is received through a rotatable holder in a centrifuge device of the apparatus. The plastic bag/receptacles are connected to the ends of these tubings and are adapted to be received in the centrifuge device for the centrifuging of fluids therein. Two tubings are adapted to be connected to hypodermic needles which are inserted in the arms of a donor of whole blood to be processed. The assembly of tubings and pressure monitors are made of inexpensive plastic so that the assembly can be discarded after it is used and a platelet separation bag has been detached from the assembly.

Blood processing assembly including a prepackaged fluid circuit module

A fluid pumping assembly includes a prepackaged, self-contained fluid circuit module which is selectively movable by an operator into and out of operative association with one or more pump rotors of an associated apparatus. The module includes a housing which supports two or more flexible conduits, which together define a prearranged fluid circuit. Portions of the flexible fluid conduits are outwardly disposed from the housing in upright, freestanding positions, even when the module is out of operative association with the pump rotors. The upright portions are purposely arranged relative to each other to facilitate only a particular operative relationship between the fluid circuit and the pump rotors when the module is subsequently moved into operative association therewith.

Fluid pumping assembly including a prepackaged fluid circuit module

A prepackaged, self-contained fluid circuit module is selectively movable by an operator into and out of operative association with one or more pump rotors. The module includes a housing which supports two or more flexible conduits, which together define a prearranged fluid circuit. Portions of the flexible fluid conduits are outwardly disposed from the housing in upright, freestanding positions, even when the module is out of operative association with the pump rotors. The upright portions are purposely arranged relative to each other to facilitate only a particular operative relationship between the fluid circuit and the pump rotors when the module is subsequently moved into operative association therewith.

Prepackaged, self-contained fluid circuit module

The blood processing method, and the apparatus for performing the steps of the method are utilized in separating whole blood into its components and include the steps of, or component parts of the apparatus for carrying out these steps of: pumping whole blood from a donor; passing the whole blood through a first chamber in a centrifuge device: centrifuging the whole blood in the centrifuge device to cause sedimentation of red blood cells from the whole blood in, and separation of platelet rich plasma from the whole blood in, the first chamber; pumping the separated platelet rich plasma from the first chamber and out of the centrifuge device where it is monitored and then back into the centrifuge device and through a second chamber in the centrifuge device where the platelet rich plasma is centrifuged to cause sedimentation of the platelets therein while passing the remaining blood fluid though the first chamber and back to the donor; recombining the plasma passed through the second chamber with the blood fluid passed through the first chamber for return to the donor; monitoring the platelet rich plasma outisde of the centrifuge device and sensing the presence of red blood cells in the platelet rich plasma; stopping and then reversing movement of the platelet rich plasma mixed with red blood cells when a mixture is sensed to return the mixture of platelet rich plasma mixed with red blood cells to the first chamber for separation of the blood components; adjusting the difference in volumetric flow rates of the pump for the whole blood pump and the pump for platelet rich plasma in response to the sensing of red blood cells; repeating the above steps until a desired volume of whole blood has been processed, and stopping operation of the centrifuge device and removing the second chamber with platelets therein from the apparatus.

Method and apparatus for processing blood

An intervivos blood processing system for centrifugally separating red blood cell and platelet components from whole blood includes a separation chamber for separating red blood cell and white blood cell components, and a collection chamber for collecting platelet components. Each chamber is formed with closely-spaced sidewalls defining respective generally flat interior chambers therebetween and is mounted on a rotatably driven carriage substantially tilted from a parallel arrangement with respect to the carriage axis of rotation at a slight angle whereby the red blood cell component is caused to collect in shoulder regions of the separation chamber and the platelet component is caused to collect on the sidewalls of the collection chamber. The processing chambers are preferably each formed from sheets of flexible hemo-compatible plastic sealed about their periphery to define the chambers therebetween, and are received on the carriage between removable carrier plates having recesses which define the shape of the chambers under fluid pressure.

Centrifugal liquid processing system

A disposable liquid applicator is provided in which the liquid to be dispensed is carried within a prescored container. Absorbent material is fastened to the container overlying the prescored portion. The container and the absorbent material cooperate to cause the liquid to be dispensed into the absorbent material when the container is bent away from the prescored portion and about itself.

Growing community of inventors

McHenry, IL, United States of America

James H DeVries