Medtronic, Inc.

Mayo Foundation for Medical Education and Research

Biolyph, LLC

Reflex Medical, Inc.

Oriel Therapeutics, Inc.

Image-guided Neurologics, Inc.

Boston Scientific Scimed, Inc.

Disetronic Licensing Ag

Federal Package Network, Inc.

Team Technologies, Inc.

Federal Molding Corp.

James Grant Skakoon

Thomas I Miller

Matthew S Solar

Kari Parmer

Charles Loeb Truwit

Rudy A Mazzocchi

John David

Frank Murdock

David Hatcher

Timothy Alan Parmer

Robert Wharen

Timothy E Pearcy

Mark Stephen Freas

James M Olsen

Mark S Lent

Benjamin A Johnson

Matthew H Adams

Patrick R Helmer

Carl D Wahlstrand

Andrew J Ries

Richard T Stone

Kenneth Timothy Heruth

John E Kast

James A Alexander

David Stuart Harris

Scott Alexander Lewis

Thomas W Ruckdeschel

Mark J Holle

David A Schuelke

Jonathan David Tuckwell

Andrew Murray Gow

Gerald A Thoe

Chad Qingshen Cai

Nicholas R Rich

Timothy Etter

Michael T Hegland

Robert E Lund

Karl Alan Jagger

Dale F Seeley

Shahn S Sage

Kevin S Fuller

Michael A Knipfer

Kurt Friedli

John R Frigstad

Thomas L Bridges

David M Lee

Gerald W Mills

Justin H Huelman

Carrie Lee Herman

Laetitia Mayor

Kristin J Malekkhosravi

Greg J Benson

Kristin J Schneider

Jim Olsen

Gary W Thompson

LEWIS;Scott Alexander

Carl Wahstrand

A topical applicator of the propel/repel type includes an expandable reservoir with a port, an attachable applicator tip, and a metered dosing system. The reservoir can be a cylindrical housing with a movable elevator movable by a drive mechanism that is initially not engaged to allow filling of a flowable compound through the port, moving the elevator. An actuator, such as a rotating ring or pushbutton may engage the drive mechanism. The drive mechanism can include a one-way ratcheting feature. Metered doses can be dispensed through a hole or holes in the applicator tip by rotating a dosing knob or pushing a pushbutton causing the drive mechanism to advance the elevator. The drive mechanism and the action to dispense metered doses can be combined into a single motion. The drive mechanism can include detent positions that correspond to discrete doses, and can also provide audible and tactile feedback.

Metered dose topical applicator

A topical applicator of the propel/repel type includes a reservoir, an attachable applicator cap, and a metered dosing system. The reservoir is suitable for mixing a topical formulation of multiple constituents using an electronic mortar and pestle and is closed using the applicator cap. Alternatively, the reservoir may be prefilled with a ready-to-use cream and medicament formulation, then sealed with a removable seal. The topical applicator can include a fast purge feature that overrides the metered dosing system to facilitate removal of air from the reservoir. The topical applicator can also include a one-way ratcheting feature to prevent reverse movement (repel) of the metered dosing system. Metered doses can be dispensed through holes in the applicator cap by rotating a knob, which has detent positions that correspond to discrete doses, and which provides audible and tactile feedback.

A reagent preparation assembly includes a body and a reaction chamber adjacent the body, the reaction chamber includes a reagent therein, such as a lyophilized reagent. An access port extends into the reaction chamber, and the access port is configured to receive an instrument. A seal extends across a portion of the reaction chamber and the access port. A reconstitution assembly is movably coupled with the body. The reconstitution assembly includes a plunger, a syringe and a piston. The plunger is movably coupled with the body. The syringe is selectively engaged with the plunger. The syringe includes a solution reservoir containing a solution, and movement of the syringe pierces the seal. The piston is selectively engaged with the plunger, and the piston is movably coupled within the syringe. Movement of the piston pushes the solution into the reaction chamber.

Reagent preparation assembly

This document discusses, among other things, examples of a low profile instrument immobilizer and means for positioning the same. In one example, the low profile instrument immobilizer grasps, secures, and immobilizes an electrode or other instrument that extends through a burr hole in a skull to a target location in a patient's brain.

Low profile instrument immobilizer

Agitator for pharmaceutical compounding

Described are various embodiments of surgical procedures, systems, implants, devices, tools, and methods, useful for treating pelvic conditions in a male or female, the pelvic conditions including incontinence (various forms such as fecal incontinence, stress urinary incontinence, urge incontinence, mixed incontinence, etc.), vaginal prolapse (including various forms such as enterocele, cystocele, rectocele, apical or vault prolapse, uterine descent, etc.), and other conditions caused by muscle and ligament weakness, the devices and tools including devices and tools for anchoring an implant to tissue.

Implants, tools, and methods for treatments of pelvic conditions

An implantable electrode paddle is adapted to receive an electrical signal from a medical device and generate an electrical field to stimulate selected body tissue. The paddle includes a housing including walls that define an interior space and a plurality of windows formed through at least a first one of the walls for transmitting the electrical field to the body tissue, an electrode array including a plurality of electrode groups, each electrode group including at least two electrodes individually secured in a respective window and spaced between about 0.1 mm and about 10 mm apart, and a plurality of wires, each of the wires being coupled to a respective electrode and routed within the interior space to receive the electrical signal. A lead assembly and an implantable medical device can include the paddle.

Field steerable electrical stimulation paddle, lead system, and medical device incorporating the same

Devices and methods provide accurate targeting, placement, and/or stabilization of an electrode or other instrument(s) into the brain or other body organ, such as to treat severe tremor or other neurological disorders. Targeting is performed using any form of image-guidance, including real-time MRI, CT, or frameless surgical navigation systems.

Device for immobilizing a primary instrument and method therefor

Growing community of inventors

Saint Paul, MN, United States of America

James Grant Skakoon