University of Colorado

Endoshape, Inc.

James Fogelberg

Michael B Lyons

Jeffrey Paul Castleberry

Robin Shandas

Julie Marie Trommeter

Malik Y Kahook

Stephen A Johnson

Naresh Mandava

Shape memory materials (SMM) are formed as coil-shaped vascular occlusion devices upon deployment. Shape memory polymer (SMP) materials are tailored through formulation for specific mechanical behavior of the coils. Concurrent coil diameter changes enhance the relative change in stiffness along the length of the coil. Interconnecting structures () are formed on ends of elongated members () in the pre-deployment shape for multiple coil insertion capability within an introducer. Channels () are formed in pre-deployment shape, elongate members () that allow access for injection of imaging contrast agent or concurrent placement of instruments. A single SMM occlusive device () transforms into multiple, smaller diameter coils () in the deployed state to generate a complex occlusive structure. A SMM occlusive device () has a collapsed fabric () component attached to and extending along a sidewall during storage and insertion, and then deploys as a coil () to form a single- or multiple-layer occlusive fabric surface within a center of the coil ().

Vascular occlusion devices

An implantable ophthalmological device () in the form of a punctal plug or canalicular implant is configured for use at or near the nasolacrimal drainage system. In a deployed state, the device () may include an elongated body (), an anchor () operably connected to the elongated body (), a radially expanding occlusive feature disposed on an outer circumference of the elongated body (), and a flange (). The elongated body () may define a lumen () configured to receive a pharmacological treatment (). The device () is made of a shape memory material such as a shape memory polymer.

Reliably retained shape memory ophthalmological implants

Growing community of inventors

Boulder, CO, United States of America

James Fogelberg