Cytonix Corporation

The United States of America, As Represented by the Secretary, Department of Health and Human Services

Applied Biosystems, LLC

Other

The United States of America As Represented by the Department of Health

Cyto-fluidics, Inc.

Conception Technologies, Inc.

James F Brown

Jonathan E Silver

Richard A Schneider

Olga V Kalinina

Thomas M Ott

A light absorbing and light emitting device, comprising a first structure supported by a holder. A first portion of the first structure (which can be flexible, sheet-like and/or at least partially opaque) comprises phosphorescent material and/or phase change material on a first side. The first structure is movable relative to the holder between a first position, in which the first side faces a first direction, and a second position, in which the first side faces a second direction. Also, a light admitting, light absorbing and light emitting assembly that comprises a light absorbing and light emitting device and a first light-transmitting structure. Also, a light absorbing and light emitting device that comprises a holder assembly and a plurality of first structures, with phosphorescent and/or phase change material, and each movable between first and second positions. Also, methods of absorbing light and emitting light with such structures.

Light absorbing and light emitting devices, light admitting assemblies, and methods of absorbing and emitting light

A projectile apparatus is provided that includes a projectile, a propellant, and optional components such as a wading, a sabot, and an intermediary device. The projectile can be fired through a barrel having a smooth bore. A sabot is provided that can include molded features, for example, a base portion and a plurality of petal portions defining, in-part, a volume for accommodating a projectile. The sabot and wadding can include molded features that control and direct gases produced by the propellant. The apparatus can convert gas pressure or gas velocity into a high rate of projectile spin. The projectile has long-range accuracy due to a high or sustainable velocity and high rate of spin.

Projectile apparatus for smooth bore barrels

An apparatus and method are provided for converting broad spectrum electromagnetic energy to useful, narrow bands of electromagnetic energy. The broad spectrum electromagnetic energy may be from the Sun or from combustion, and output from the apparatus may be bands of visible light, infrared, microwaves, or a combination thereof. The apparatus can function as part of a highly efficient plant growing system or may function as part of a heating or warming system.

Apparatus for converting broad band electromagnetic energy to narrow band electromagnetic energy

A method of making a projectile apparatus is provided that includes making one or components of the apparatus using an additive manufacture technique such as 3-D printing or laser-aided additive manufacture. The projectile apparatus can have a projectile, a propellant, and one or more optional components such as a wading, a sabot, and an intermediary device. The projectile can be fired through a barrel having a smooth bore. Additive manufacture methods can be used that involve forming components from superalloys having nanoparticles incorporated therein. The projectile apparatus can convert gas pressure or gas velocity into a high rate of projectile spin. The projectile has long-range accuracy due to a high or sustainable velocity and high rate of spin.

High spin projectile apparatus comprising components made by additive manufacture

High spin projectile apparatus for smooth bore barrels

A method for amplifying a target nucleic acid present in a sample includes introducing, via an entrance opening of a planar fluidic assembly, a sample containing one or more target nucleic acids into a flow channel of the planar fluidic assembly, the flow channel extending from the entrance opening to an exit vent and having a substantially uniform cross-section. A plurality of nucleic acid primers that are complementary to a portion of the one or more target nucleic acids are disposed at locations within and along the flow channel. The method further includes subjecting the sample introduced into the flow channel to a primer-based amplification reaction using the nucleic acid primers, wherein the primer-based amplification reaction produces amplified product of the one or more target nucleic acids, and retaining the amplified product at one or more of the locations within the flow channel during the primer-based amplification reaction. The method also includes detecting localized accumulation of the retained amplified product, the localized accumulation occurring at the one or more locations.

Device and method for amplifying target nucleic acid

Substrates, surfaces, assemblies, kits, compositions, and methods are provided for forming touch screens and other appliance surfaces exhibiting good hydrophobicity, oleophobicity, and abrasion resistance. Methods are provided for increasing a population density of hydroxyl groups on a touch surface of a touch screen substrate without affecting the compressive strength of the back surface. The treated touch surface of the substrate can then be coated with a coating that includes an organo-metallic and/or silane, for example, a fluorosilane such as a perfluoropolyether alkoxysilane. A substrate can retain its compressive resistance to breakage by impact applied to the touch surface while minimizing any decrease in compressive strength against impact against the touch surface. Examples of such substrates include touch screens for mobile and desktop electronic devices, components of 3D display devices, and components for electrowetting display devices.

Low surface energy touch screens, coatings, and methods

A method comprises loading a sample portion into a sample chamber which comprises means for minimizing diffusion of the sample portion, subjecting the sample portion to an amplification step, and determining whether the sample portion contains at least one molecule of a target nucleic acid. If the sample portion contains a single molecule of the target nucleic acid, the sample portion would attain a detectable concentration of the target nucleic acid after a single round of amplification. Also, a microfluidic device comprising a sample portion and a sample chamber comprising means for minimizing diffusion of the sample portion. Also, a microfluidic device comprising a sample chamber and an amplification targeting reagent positioned in the first sample chamber.

Method for detecting the presence of a target nucleic acid sequence in a sample

A device for amplifying target nucleic acid in a sample can include a planar fluidic assembly including a transparent substrate, a porous material layer on a surface of the transparent substrate, and a cover over the porous material layer and sealingly affixed to the substrate. The cover may be spaced from the porous material layer and a flow channel defined between the porous material layer and the cover. The flow channel may have a uniform cross-section from a first end to a second end. The assembly can further include an inlet in flow communication with the first end of the flow channel to introduce sample containing target nucleic acid into the flow channel, an outlet in flow communication with the second end of the flow channel, and a plurality of nucleic acid primers retained by the porous material layer at discrete regions along and within the flow channel, each of the plurality of nucleic acid primers being complementary to a portion of the target nucleic acid in the sample to enable a primer-based amplification reaction of the target nucleic acid. The porous material layer may be configured to retain, at the discrete regions and during a primer-based amplification reaction, sample introduced to the flow channel and amplified product of the amplification reaction.

Device for amplifying target nucleic acid

A system and method is shown for coating an article, including a chamber that can be at least partially open to surrounding air to allow free flow of air through the chamber and recovery of vapor produced during a coating operation within the chamber. The chamber can include a support surface that is adapted to support the article during a coating process, and a coating device within the chamber can be adapted to selectively apply a coating of a fluorocarbon in a fluorinated solvent to at least a portion of an article supported on the support surface.

Method of treating an article with a fluorocarbon

Hydrophobic coating compositions are provided as are processes to coat articles with the compositions. Extremely hydrophobic coatings are provided by the compositions. Durable, weatherable and scratch-resistant coatings are provided by compositions comprising a fluorinated component and an adhesion promoter compound. The adhesion promoter compound can include an alkoxy group, a furfuryl-containing ring structure, and a reactive group.

Hydrophobic coating compositions and articles coated with said compositions

Hydrophobic coating compositions are provided as are processes to coat articles with the compositions. Extremely hydrophobic coatings are provided by the compositions. Compositions that include perfluorohexyl(meth)acrylate and a branched or high Tg monomer are provided as are articles coated with the polymerization product of the composition. Methods are also provided for forming hydrophobic coatings on articles.

A method comprising subjecting one or more sample portion(s) to a single amplification step, thereby amplifying a single molecule in the sample portion to a detectable level, and, in some embodiments, then determining whether the sample portion contains at least one molecule of the target nucleic acid. In some embodiments, the sample portion is in a porous sample structure, or in a sample chamber which comprises means for minimizing diffusion of the sample portion, or in a sample chamber which is inside a microcapillary device, or in a sample retaining means.

Growing community of inventors

Clifton, VA, United States of America

James F Brown