Smithkline Beecham Corporation

Other

Chiron Corporation

Albert Einstein College of Medicine

Smithkline Beckman Corporation

James E Strickler

Jerry Leroy Adams

Timothy Francis Gallagher

Peter R Young

Peter C McDonnell

Dean E McNulty

John Richard Heys

David W Green

John C Lee

Martin M Rosenberg

James A Fornwald

Dean P Taylor

Thomas R Berka

John Cheung-Lun Lee

Joselina G Gorniak

Jeffrey E Strickler

Mary Kim Warren

Judit Csejtey

Albert Boosman

E Richard Stanley

Kenneth J Wilson

This invention relates to drug binding proteins, to genes encoding same and to assays and methods for screening pharmaceuticals. More specifically, this invention relates to a Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding protein, to a gene encoding same and to assays and screens useful in the evaluation and characterization of drugs of this pharmacologic class.

Antibodies produced against cytokine suppressive anti-inflammatory drug binding proteins

Polynucleotides encoding cytokine suppressive anti-inflammatory drug

Screening methods using cytokine suppressive anti-inflammatory drug

The present invention relates to the purification of proteins, to the products of such purification, and to DNA probes constructed therefrom. More specifically, the invention relates to the purification and sequencing of murine and human colony stimulating factor-1 (CSF-1).

Purified human CSF-1

Cytokine suppressive anit-inflammatory drug binding proteins

Oligonucleotides comprising a region of a cytokine suppressive

This invention relates to a process for producing a heterologous polypeptide in Streptomyces which involves transforming a Streptomyces organism with a recombinant DNA molecule comprising an LEP-10 of LTl sequence selected from the group consisting of a sequence encoding a gene expression unit, a promoter sequence or an export control encoding sequence each operatively linked to a heterologous coding sequence and then culturing the transformed Streptomyces such that the heterologous polypeptide is expressed.

Protein protease inhibitors from streptomyces

This invention relates to novel protein protease inhibitors as well as DNAs encoding same and vectors and transformed host cells useful for the recombinant production of the inhibitors.

A container and follow plate assembly for highly viscous materials such as hand cleaner is selectively usable with dispensing devices having receiving ports of larger and smaller sizes. The preferably cylindrical container, which is sized so that one end fits the larger port, has a removable cover at that end and a fixed member closing the second end. The fixed member inlcudes a removably covered discharge opening therein which fits the smaller port. The follow plate, a one piece, preferably circular dish which is closely spaced from the inside of the container, is positioned adjacent the discharge opening end when the container is filled. The follow plate includes an integral but removable section aligned with and larger than the discharge opening.

Container and follow plate assembly usable with viscous material

Growing community of inventors

Milton, MA, United States of America

James E Strickler