W. L. Gore & Associates, Inc.

Gore Enterprise Holdings, Inc.

W. L. Gore & Assoc. Inc.

James D Silverman

Edward H Cully

Craig W Irwin

Dustin C Burkart

Cody L Hartman

Jeffrey B Duncan

Bret J Kilgrow

Alexander K Koss

Joseph R Armstrong

Larry J Kovach

Mark Y Hansen

Tyson J Skelton

Criag W Irwin

Edward Emil Shaw

James L Goepfrich

Paul D Goodman

Brandon C Hedberg

Stanley L Mish

Roark N Wolfe

Michael J Shepard

Jason D Hemmer

Olga Baykova

Jared S Nelson

Brett J Wham

Kehinde A Majolagbe

Nathan C Korey

Aaron D Fox

Keith O Rust

Parikshith K Kumar

Zachary A Crannell

Joshua D Cross

Jeffrey Kennington

Elton R Migliati

Bryan Reep

Richard D Strones

Brian L Souter

Debra K Born

Robert M Depue

Scott M Bryson

Theodore H Chang

Brian L Johnson

Crag W Irwin

Edward E Shaw

The present disclosure comprises devices, systems, and methods having an inverted sheath configured to cover, and in some instances constrain, a medical device and to retract through eversion, thus enabling the deployment of medical device at the treatment site. A constraining sheath can evert hydraulically. A constraining sheath can be configured to neck down a medical device to achieve a lower delivery profile. Furthermore, a constraining sheath can comprise a balloon to expand or positionally or structurally adjust a medical device.

Evertable sheath devices, systems, and methods

A medical device deployment apparatus that employs a first actuation line and a second actuation line, whereby a delay is sought between initiation of the actuation of the first actuation line and actuation of the second actuation line. Prior to actuation, the first actuation line includes sequentially aligned multiple loops, wherein the multiple loops provide predefined slack to delay linear actuation of the first actuation line when tension is applied to both the first and second actuation lines.

Actuation line storage systems and methods

Various aspects of the present disclosure are directed toward implantable medical devices that include a frame and a tubular member attached to the frame. The tubular member includes one or more fibrils or a strength in alignment with one or more struts of the frame.

Matched stent cover

A stent incorporating flexible, preferably polymeric, connecting elements into the stent wherein these elements connect adjacent, spaced-apart stent elements. Preferably the spaced-apart adjacent stent elements are the result of forming the stent from a helically wound serpentine wire having space provided between adjacent windings. Other stent forms such as multiple, individual spaced-apart ring-shaped or interconnected stent elements may also be used. The connecting elements are typically web-shaped and result from creating slits or apertures in a covering of graft material applied to the stent and then, for example, applying heat to cause the slits or apertures to enlarge. The remaining graft material forms the interconnecting webs between the adjacent stent elements.

Stent having adjacent elements connected by flexible webs

An implantable medical device deployment system is disclosed that employs both a sheath element and a constraint member to protect implantable medical devices during delivery in a body while providing simple, accurate, and reliable device deployment. The delivery system is configured so that loading and deployment forces are not directly related to device diameter, length, or design, thus allowing a more universal delivery system across various delivered device configurations and product lines. The deployment system can provide numerous benefits, include better protection for drug-coated implantable devices.

Implantable medical device constraint and deployment apparatus

A wire of a nickel-titanium alloy having a permanent set of less than 5% when 11% strain is applied to the wire is disclosed. The wire may be formed by applying a first heat treatment to the wire, the first heat treatment includes applying heat of a first temperature for a first period of time, applying a strain deformation to the wire to set a shape for the wire during the first heat treatment, and applying a second heat treatment to the wire. The second heat treatment includes applying heat of a second temperature different from the first temperature for a second period of time, and the second temperature is between 210° C. and 290° C. The wire may have a modulus of at least 53 GPa when 200 MPa of stress is applied to the wire, and the wire is bonded to a secondary component.

Wires of nickel-titanium alloy and methods of forming the same

Various aspects of the present disclosure are directed toward implantable medical devices, systems, and methods for cardiac assistance.

Implantable ventricular assist devices and methods

A medical device frame including an undulating frame element defining a series of peaks each defining a longitudinal splay angle, circumferential cant angle, or combinations thereof. In some examples, the series of peaks are non-overlapping when the frame is in an expanded configuration and overlap when the frame is in the collapsed configuration. The longitudinal splay angle and/or circumferential cant angle may remain relatively unchanged between the expanded and collapsed configurations (e.g., within about 15%).

Expansion members for implantable devices and associated systems and methods

Various aspects of the present disclosure are directed toward apparatuses, systems and methods that include a self-expanding endoprosthesis having a reduced configuration and a deployed configuration. The self-expanding endoprosthesis may include a self-expanding stent element having an enlarged diameter and a graft component attached to at least a portion of the self-expanding stent element and having an enlarged diameter less than the enlarged diameter of the self-expanding stent element in the deployed configuration.

Pre-strained stent elements

An open stent (a stent having open space through its thickness at locations between the ends of the stent), incorporating flexible, preferably polymeric, connecting elements into the stent wherein these elements connect adjacent, spaced-apart stent elements. Preferably the spaced-apart adjacent stent elements are the result of forming the stent from a helically wound serpentine wire having space provided between adjacent windings. Other stent forms such as multiple, individual spaced-apart ring-shaped or interconnected stent elements may also be used. The connecting elements are preferably longitudinally oriented.

Stent having flexibly connected adjacent stent elements

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Flagstaff, AZ, United States of America

James D Silverman