Eastman-kodak Company

Ortho-clinical Diagnostics, Inc

Johnson & Johnson Clinical Diagnostics, Inc.

Revolution Lighting Technologies, Inc.

Other

James D Shaw

Merrit Nyles Jacobs

Martin F Muszak

Raymond Francis Jakubowicz

James Samsoondar

David Angelo Tomasso

Michael W LaCourt

Michael Avdenko

Davis Freeman, Iii

Thomas Moffett

Nicholas Want

Stuart Gilmour MacDonald

Zhong Ding

Scott H Schwallie

Donald James Moran, Jr

Dale Robert Ryan

James Daniel Riall

David Donald Hyde

Russel H Marvin

David M Charneski

Joseph John Dambra

Alan J Lowne

Randy Kristopher Bower

Ronald F Brookes

Thomas Arter

Christopher Michael Parobek

Nicholas VanBrunt

James A Love

Lee William David

Malinda L McFeaters

David A Heavner

Gary A Graham

Michael P Tuszynski

Mark Alan Simon

James Hassett

Michael W La Court

Robert T Witkowski

Merritt N Jacobs

An LED luminaire with an integrated battery backup is divided into a hidden infrastructure portion and a decorative body portion. The luminaire body has a main lighting deck with two separate LED arrays mounted thereon and a decorative skirt extending from the main lighting deck. A first LED array is operative on regular and emergency power, and a second LED array is operative on battery power. A diffuser panel is received over the main lighting deck. The hidden infrastructure portion includes a light fixture housing configured and arranged to be mounted within a building infrastructure, an emergency battery backup assembly received within the light fixture housing wall, and a housing fixture bracket secured within the light fixture housing to support the emergency backup assembly in the upper portion of the light fixture housing.

LED luminaire with integrated battery backup

An LED luminaire with an integrated battery backup is divided into a hidden infrastructure portion and a decorative body portion. The luminaire body has a main lighting deck with at least one LED mounted thereon and a decorative skirt extending from the main lighting deck. A diffuser panel is received over the main lighting deck. The hidden infrastructure portion includes a light fixture housing configured and arranged to be mounted within a building infrastructure, an emergency battery backup assembly received within the light fixture housing wall, and a housing fixture bracket secured within the light fixture housing to support the emergency backup assembly in the upper portion of the light fixture housing.

The invention is a method for detecting failures in an analyzer for conducting clinical assays. Potential errors that can result in assay failures in an analyzer are identified, as are their potential sources. The probability that an error source so identified will result in a clinically significant error is also determined. Available potential detection measures corresponding to the source of potential errors are identified with a combination of such measures selected and implemented based on their probability of detecting such errors within an acceptable limit with a concomitant low probability of the false detection of an assay failure. Each of the measures selected are functionally independent of others chosen to address the source of the error and are not subject to the same inherent means of failed detection. Applications of the method in a clinical analyzer are also presented.

Failure detection in automated clinical analyzers

A clinical analyzer for determining the presence or amount of an analyte in a sample includes at least one reagent supply and at least one reaction containment device for containing a volume of sample and a volume of said at least one reagent from said at least one reagent supply. A wash-free delivery system introduces reagent into at least one reaction containment device without requiring washing of delivery components.

Chemistry system for clinical analyzer

A closure for a container includes: (a) an inner cylindrical wall having first and second ends and defining a space; (b) an outer cylindrical wall opposite the inner cylindrical wall and having the first and second ends to form an outer surface of the closure; (c) a first end wall extending across said first end, wherein the first end wall comprises a recess extending a least partially into the space, and a first set of threads disposed on the recess. An apparatus usable on a diagnostic analyzer container and includes: a threaded rotatable spindle adapted for threading into a closure having a threaded depression and for applying a rotational force to remove the closure; and a clutch having an element adapted to engage the closure and apply a rotational to the closure.

Container closure and device to install and remove closure

A metering tip for use in a clinical analytical apparatus includes a tapered body having at least one interior stepped areas. Each of the stepped areas include a sharp diametrical edge for latching a fluid meniscus being dispensed from the tip and for reducing fluid oscillation during metering.

Metering tip with internal features to control fluid meniscus and oscillation

A sample handler includes a plurality of sealable metering tips, each of the tips, when sealed, containing a fluid volume of a test fluid and in which each of the sealed metering tips acts as an auxiliary sample supply container for use with at least one chemistry system of a clinical analyzer.

Auxiliary sample supply for a clinical analyzer

Evaporation control for a fluid supply, such as used in a clinical analyzer, can be provided by utilizing a straw-like insert which is disposed into a fluid-containing bottle. The straw provides an increased diffusion length or 'stagnant' zone. The bottle can also be configured to effectively reduce evaporation in a similar manner by providing a narrowed diameter prior to the fluid retaining portion of the bottle and by increasing the distance between the top of the bottle and the top of the fluid surface.

Evaporation control for a fluid supply

A system for detecting and analyzing patient sample quality and/or analytes, while the sample is in the metering tip used to aspirate the sample liquid from an original patient sample container, and also to dispense the liquid onto a slide test element. Spectrophotometric analysis may be done on the sample liquid while it is still in the tip which has been converted into a cuvette. One technique for such analysis is by scanning the cuvette for transmittance in a light-tight enclosure. Near-infrared and adjacent visible radiation may be used, and the absorption spectra of the liquid detected and analyzed. A possible aspect of the present invention relates to enhancing throughput of an analyzer by conducting a sample quality measurement in a process that is parallel to the main analyzer timing cycle. Another possible aspect of the present invention relates to improving performance of the analyzer by sealing the end of the metering tip to spontaneously form a cuvette for holding the sample during the sample quality measurement. Some advantages of the present system and method include improved throughput, the capability to use smaller sample liquid volumes, eliminating any need for a separate supply of cuvettes independent of the metering tips, and providing for detection through a cone of the metering tip rather than through any label, compared to doing the scanning of the sample liquid in a primary patient collection container.

Analyzer with sample quality measurement, and method

Chemistry system for a clinical analyzer

Analysis method with sample quality measurement

A method and apparatus for detecting improper liquid content of a metering tip of an analyzer. The method detects the content or status using radiation between 630 and 2000 nm, and comprises the steps of: a) aspirating the liquid into the tips; b) scanning the liquid; c) providing relative motion between the tip and the scanner while simultaneously scanning the liquid; d) detecting the amount of light transmitted to detector at all levels of the liquid; e) comparing the detected light with light known to be transmitted at levels of liquid free of air bubbles; and flagging the results.

Incremental absorbance scanning of liquid in dispensing tips

Apparatus and method for detecting patient sample quality, and/or analytes, in the tip used to aspirate the patient sample liquid and then dispense it onto a slide test element. Spectrophotometric analysis is done on the liquid while still in the tip, by scanning the tip for transmittance in a light-tight enclosure, using NIR and adjacent visible radiation, and detecting the absorbance spectra of the liquid. Thereafter, or prior thereto, the liquid is dispensed onto a dried slide test element for assaying analytes that are not assayed spectrophotometrically, thus enhancing throughput.

Analyzer throughput featuring through-the-tip analysis

Apparatus and method for detecting patient sample quality, and/or analytes, in the tip used to aspirate the patient sample liquid and then dispense it onto a slide test element. Spectrophotometric analysis is done on the liquid while still in the tip, by scanning the tip for transmittance in a light-tight enclosure, using NIR and adjacent visible radiation, and detecting the absorbence spectra of the liquid. Much smaller liquid volumes, and no through-the-label detection, are required, compared to doing the scanning of the liquid in a primary patient collection container.

Sample quality measurement and/or analyte measurement in the dispensing

A chain incubator or conveyor, and method of use in an analyzer, wherein an endless chain is formed of repeating members and each comprising a link, element support, a cover, and means for biasing the cover onto the support with an article such as a test element between them. The members are linked together by a pair of pivot pins, and the chain is engaged by a drive sprocket and an idler sprocket.

Chain incubator/conveyor and method of use

Growing community of inventors

Hilton, NY, United States of America

James D Shaw