Baxter International Inc.

Intertherapy, Inc.

Baxter Travenol Laboratories, Inc.

James D Passafaro

Henry Nita

Douglas H Gesswein

Robert James Siegel

James M Griffith

James M Gessert

Paul J Zalesky

Viet P Dinh

A catheter device incorporating combined ultrasound ablation and balloon dilation components. The catheter device generally comprises an elongate catheter body having proximal and distal ends and an outer surface. Disposed on the outer surface of the catheter body is a dilation balloon. At least one balloon inflation lumen fluidly connects the proximal end of the catheter body to the dilation balloon to permit injection of inflation fluid into the dilation balloon. Extending longitudinally through the catheter body is an ultrasound transmission member having a proximal end and a distal end, with the proximal end being connectable to an ultrasound transducer such that ultrasonic energy will pass through the ultrasound transmission member to the distal end thereof. In alternative embodiments of the present invention, there are provided catheter devices incorporating combined ultrasound ablation and laser ablation components as well as combined ultrasound ablation and atherectomy ablation components.

Angioplasty and ablative devices having onboard ultrasound components

An ultrasound catheter for removing obstructions from tubular anatomic structures such as blood vessels, said catheter comprising an elongate flexible catheter body having an ultrasound transmission member or wire extending longitudinally therethrough. A distal head is formed on the distal end of the ultrasound transmission member or wire and is affixed to the catheter body. The ultrasound transmission member or wire may be formed of any material capable of transmitting ultrasonic energy including various superelastic metal alloys such as nickel titanium metal alloys. The distal portion of the ultrasound transmission member or wire may be of reduced diameter to provide enhanced flexibility and/or amplification of the ultrasonic energy through the distal portion of the ultrasound transmission member or wire. A proximal end connector may be provided with a sonic connector to effectively couple the catheter to the ultrasound transducer.

Ultra-sound catheter for removing obstructions from tubular anatomical

An intravascular ultrasonic imaging probe includes a transducer subassembly adapted to being rotated within a guide catheter via a drive cable. The guide catheter establishes a bearing surface for supporting the transducer subassembly during rotation while also mechanically isolating the rotating transducer subassembly from surrounding tissue (thereby protecting the tissue from inadvertent and/or undesired tissue abrasion by the subassembly during rotation). The catheter is positioned within a vessel to be imaged by telescopically advancing the same over a previously positioned guide wire, the guide wire being withdrawn after the guide catheter is positioned. Thereafter, the imaging probe is inserted into the guide catheter and operated so as to obtain ultrasonic images of the vessel under investigation.

Intravascular ultrasonic imaging probe and methods of using same

Intravascular probe assemblies are provided with both ultrasonic imaging and laser ablation (angioplasty) capabilities. In preferred embodiments, the probe assemblies will include a distally positioned rotatable housing having an ultrasonic transducer and an optical fiber operatively fixed therein so as to respectively emit acoustic energy and laser radiation along a common path generally parallel to the housing's axis, but in opposing axial directions. An optical and acoustic reflector is interposed between the transducer and optical fiber so as to redirect incident acoustic energy and laser radiation generally radially with respect to the housing.

Medical probe assembly having combined ultrasonic imaging and laser

Accurate in vivo measurement of blood oxygen saturation by fiberoptical means is made possible throughout a wide range of hematocrit or total hemoglobin values by using a single R/IR ratio I and calculating the SO.sub.2 value therefrom through the use of a second-order polynomial of the form

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Santa Ana, CA, United States of America

James D Passafaro