Oregon State University

State of Oregon

James D Ingle

Robert J Miller

A device for detecting substances in a liquid film by measuring chemiluminescence, fluorescence or absorption using techniques such as flow-injection analysis schemes, liquid chromatographies, and gas chromatographies. The device can be used as a micro-volume mixing or reaction substrate for a variety of measurements. The device comprises at least two film supports that are separated by a small gap. One or more applicators are positioned along the gap to supply fluids to the gap. The applicators are positioned near the gap at a spacing that is near the necking length of the fluid supplied by the applicator. A thin, continuous film of the mixture of fluids to be examined is supported in the gap between the film supports. The film extends through the examining chamber and through drop and overflow detection probes. Also disclosed is a mixing or reaction chamber which comprises an enclosable mainframe into which a plurality of applicators are butted near a gap defined between two film supports. The chamber communicates with an inlet port and an exit port for controlling the pressure and other aspects of the environment in the chamber.

Observation cell and mixing chamber

A windowless flow cell for detecting substances in a flowing fluid stream by chemiluminescence, fluorescence or absorption in flow injection analysis schemes, liquid chromatographs, or gas chromatographs is described. Furthermore, the mixing characteristics of the invention suggest its use as a micro-volume mixing chamber for a variety of experiments. A windowless flow cell comprising an upper body plate, upper wire spacer, mid-body plate, lower body spacer plate, and lower body plate interconnected by anchor bolts is described. Cell wires are attached to the upper body plate and the lower body plate. A primary reagent port through the upper body plate, with secondary reagent port and tertiary reagent port through the mid-body plate provide the fluids to be mixed. A thin film of the mixture of fluids to be examined flows down the cell wires through the examining chamber and through the drop detector and overflow detector prior to exiting the drain port by way of a low vacuum source. A micro-volume mixing chamber comprising a plexiglass mainframe with viewing windows of an examining chamber into which a plurality of reagent ports flow to form a fluid film on cell wires is described. The examining chamber also comprises gas inlet ports for control of pressure and of the type of gas environment.

Growing community of inventors

Corvallis, OR, United States of America

James D Ingle