Medtronic Minimed, Inc.

James D Holker

John Joseph Mastrototaro

William P Van Antwerp

Guillermo A Calle

Nannette M Van Antwerp

Kevin Branch

Rajiv Shah

Udo Hoss

Rebecca K Gottlieb

Gopikrishnan Soundararajan

Embodiments of the invention provide electrochemical analyte sensors having elements designed to modulate their electrochemical reactions as well as methods for making and using such sensors.

Amperometric sensor electrodes

A sensor and method of making the same for implantation in a body that includes a substrate with notches cut in the substrate to form a necked down region in the substrate; and at least one sensor electrode formed from one or more conductive layers. Preferably, the thickness of the substrate ranges from approximately 25&#x3bc; to 350&#x3bc;, but the thickness of the substrate can range from 5&#x3bc; to 750&#x3bc;. The sensor may be incorporated in to a sensor assembly includes a slotted needle having a slot. The notches creating the necked down region allow the substrate to slide into the slotted needle, which that has the slot narrow enough to permit passage of the necked down region. However, a non-necked down region of the substrate is prevented from pulling out of the slotted needle through the slot. The slot of the slotted needle may also permit the necked down region of the substrate to slide down the slot.

Analyte sensor method of making the same

Glucose sensor

A method of making a sensor includes the steps of providing a preformed self-supporting flexible substrate; sputter-depositing a metal layer on the substrate; etching the sputter-deposited metal layers to form a sensor electrode having a proximal segment and a distal segment; plating a metal layer on the sensor electrode; and separating the sensor electrode and at least a portion of the substrate underlying the sensor electrode from the remainder of the substrate. Sensors prepared according to the inventive methods, and sensor sets including the sensors, are also provided.

Analyte sensor and method of making the same

Growing community of inventors

Alta Loma, CA, United States of America

James D Holker