The Children's Hospital of Philadelphia

James Christopher Edgar

Timothy P L Roberts

Timothy Pl Roberts

Methods using measuring alpha activity in the brain are provided for the detection and/or diagnosis of a mild traumatic brain injury in a subject. The methods comprise measuring an alpha activity in the brain of a subject, wherein an increase in the alpha activity in the brain of the subject compared to control subjects without a brain injury or to a baseline of the subject is indicative of the subject having the mild traumatic brain injury. The alpha activity may be measured when the subject is in a resting state. The methods may further comprise administering a therapy such as a pain or headache medication to the subject with a mild traumatic brain injury.

Methods for the detection of brain injury

Methods for screening for therapies against autism spectrum disorders and methods for determining whether a subject would be responsive to a therapy against an autism spectrum disorder are disclosed.

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Philadelphia, PA, United States of America

James Christopher Edgar