Alexza Pharmaceuticals, Inc.

Concert Pharmaceuticals, Inc.

James Cassella

Daniel J Myers

Edwin S Kamemoto

Lily Gong

Philip B Graham

Jana Von Hehn

Colleen E Hamilton

Amanda T Wagner

Virginia Braman

Khe Kubel

Vinita Uttamsingh

Alprazolam formulated as an inhaled condensation aerosol and method for treating epilepsy and/or seizures.

Method of treating epilepsy

The disclosure teaches the use of antistatic materials in the airway for thermal aerosol generation devices. The present disclosure teaches the use of antistatic materials for drug delivery in any drug that may be susceptible to charging during aerosol generation.

Use of antistatic materials in the airway for thermal aerosol condensation process

The present disclosure relates generally to the field of nicotine delivery. The disclosure teaches a nicotine meta-salicylate. More specifically, the disclosure teaches a condensation nicotine aerosol where nicotine meta-salicylate is vaporized. This disclosure relates to aerosol nicotine delivery devices. The delivery devices can be activated by actuation mechanisms to vaporize thin films comprising a nicotine meta-salicylate. More particularly, this disclosure relates to thin films of nicotine salt with meta salicylic acid for the treatment of nicotine craving and for effecting smoking cessation.

Nicotine salt with meta-salicylic acid and applications therein

Disclosed is a method of treating in a subject hair loss disorders that are beneficially treated by administering a JAK1 and/or JAK2 inhibitor. The method comprises administering to the subject an amount in the range of about 4 mg to about 50 mg of Compound (I), or a pharmaceutically acceptable salt thereof. This invention also provides compositions comprising Compound (I) and the use of such compositions in the described methods. 

Treatment of hair loss disorders with deuterated JAK inhibitors

Nicotine salt with meta-salicylic acid

Growing community of inventors

Essex, CT, United States of America

James Cassella