Monsanto Technology LLC

Monsanto Company

Pharmacia Corporation

G.d. Searle LLC

James C Peterson

Juan Pedro Arhancet

David A Morgenstern

Howard C Berk

William L Moench, Jr

Samuel J Tremont

Thaddeus S Franczyk, Ii

Mark John Pozzo

Jon P Lawson

Claire A Przybyla

Kevin J Koeller

Robert B Weisenfeld

Payman N Farid

Kevin Babiak

Pierre-Jean Colson

Benxin Zhi

Robert Hett

Grace Mary Wagner

Jay S Trivedi

Andrew Carpenter

Shine Chou

Lawrence M Miller

Christian H Huber

Vladislav Orlovski

Eduardo K Mar

Gerald A Weisenburger

James J Li

Sherrol L Baysdon

Melvin L Rueppel

Jerry D Clark

Yinong Ma

Jimmy W Worley

Ajit S Shah

Lefteris Patelis

James Li

William L Moench

This invention is directed a process for preparation of a carboxylic acid salt by dehydrogenation of a primary alcohol. The invention is also directed to a catalyst for dehydrogenating primary alcohols. In one embodiment, for example, the catalyst comprises a metal support (preferably a metal sponge support) having a copper-containing coating at the surface thereof. In another embodiment, the catalyst comprises a metal selected from the group consisting of zinc, cobalt, iron, tin and combinations thereof having a copper-containing coating at the surface thereof.

Process for preparation of a carboxylic acid salt by dehydrogenation of a primary alcohol

This invention is directed to a process for making a salt of a carboxylic acid. The process comprises contacting a catalyst with an alkaline mixture comprising a primary alcohol. In one embodiment, for example, the catalyst comprises a metal support (preferably a metal sponge support) having a copper-containing active phase at the surface thereof. The support is resistant to deformation under the conditions of the dehydrogenation reaction. In another embodiment, the catalyst comprises a metal sponge having a copper-containing active phase at the surface thereof and a supporting structure containing at least 10% non-copper metal. This invention is also directed to copper-containing catalysts which may, for example, be used in the above process. This invention is further directed to processes for making such catalysts.

Process and catalyst for dehydrogenating primary alcohols to make carboxylic acid salts

This invention is directed to a process for making an iminodiacetic acid compound from a monoethanolamine substrate having the formula: wherein Ris hydrogen, hydrocarbyl, or substituted hydrocarbyl. The process includes a series of reactions comprising a cyanomethylation, a hydrolysis and a dehydrogenation. In a particular embodiment, the iminodiacetic acid produced is disodium iminodiacetic acid and the monoethanolamine substrate used is 2-aminoethanol.

Process for making iminodiacetic acid compounds from monoethanolamine substrates

Among its several embodiments, the present invention provides an improved process for the preparation of tetrahydrobenzothiepine-1,1-dioxide compounds; the provision of a process for preparing a diastereomeric mixture of tetrahydrobenzothiepine-1,1-dioxide compounds from a single diastereomer of such compounds; the provision of a process for the preparation of 3-bromo-2-substituted propionaldehyde compounds; and the provision of a process for the preparation of 3-thio-2-substituted propionaldehyde compounds.

Method for the preparation of tetrahydrobenzothiepines

This invention is directed to a process for dehydrogenating primary alcohols to make salts of carboxylic acids. The process comprises contacting a catalyst, preferably a metal support coated with copper or silver, with an alkaline mixture comprising a primary alcohol. The invention further provides for novel copper-containing and silver-containing catalysts which may be used, for example, in the above process as well as processes for making such catalysts.

Catalyst for dehydrogenating primary alcohols to make carboxylic acid salts

Synthesis of a hydrazone .beta.-keto ester by the reaction with a diazo

This invention relates to a process for the preparation of N-phosphonomethylglycine and its salts. More particularly, this invention is directed to a method for preparing N-phosphonomethylglycine involving the reaction of AMPA, an alkali metal cyanide or hydrogen cyanide, and formaldehyde and hydrolyzing the product of that reaction to form N-phosphonomethylglycine and its salts.

Method for producing N-phosphonomethylglycine and its salts

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Manchester, MO, United States of America

James C Peterson