Candela Corporation

Candela Laser Corporation

USA As Represented by Secretary of the Navy

Boston University

The United States of America

New England Medical Center Hospitals. Inc.

Massachusetts General Hospital Corporation

James C Hsia

Christopher J Jones

Jayant D Bhawalkar

Dilip Y Paithankar

Kathleen McMillan

R Rox Anderson

Rafael Armando Sierra

Kevin Schomacker

Anthony J Durkin

Edward Victor Ross

Anthony D Quaglia

Horace W Furumoto

Xiaoming Shang

Michael G Clancy

Jinze Qiu

Charles Johnson

Joseph A Lowery

Shlomo Melamed

Karl Pope

Mike Clancy

Harry L Ceccon

Scott F Mogren

Oon T Tan

Yacov Domankevitz

Stanley M Shapshay

Robert Schlier

Constantinos Demetriou

Christopher Jones

Paithankar Y Dilip

An apparatus for treatment of a subcutaneous fat region includes a source of electromagnetic radiation generating electromagnetic radiation having a non-fat selective wavelength. A delivery system is coupled to the source of electromagnetic radiation and is configured to deliver the electromagnetic radiation to the subcutaneous fat region for at least 300 seconds. A controller is configured to adjust an average power density based on a thickness of skin overlying the subcutaneous fat region, and to cause necrosis of at least one fat cell in the subcutaneous fat region. The non-fat selective wavelength is 950 nm to 1090 nm, 1100 nm to 1160 nm, 1,300 nm to 1625 nm, or 1,800 nm to 2,200 nm.

Reduction of pain through lower fluence rates and longer treatment

A MOPA laser system that includes a seed laser configured to output pulsed laser light, an amplifier configured to receive and amplify the pulsed laser light emitted by the seed laser; and a pump laser configured to deliver a pump laser beam to both the seed laser and the amplifier.

Laser systems and related mehtods

A method of treating a subcutaneous fat region is provided. The method includes generating electromagnetic radiation having a wavelength of about 1,200 nm to about 1,230 nm and delivering an average power density of less than or equal to about 2.3 W/cmof the electromagnetic radiation to the subcutaneous fat region for at least 300 seconds. The method also includes cooling an epidermal region and at least a portion of a dermal region overlying the subcutaneous fat region for at least a portion of the at least 300 seconds. The method further includes causing necrosis of at least one fat cell in the subcutaneous fat region.

Laser systems and related methods

A treatment for subcutaneous fat and/or cellulite includes delivering a beam of radiation to a subcutaneous fat region disposed relative to a dermal interface in a target region of skin. The beam of radiation affects at least one fat cell in the subcutaneous fat region without causing substantial unwanted injury to the epidermal region and causes thermal injury to a dermal region to induce collagen formation to strengthen the target region of skin in a target region of skin. The treatment can include cooling an epidermal region of the target region of skin.

Apparatus for treating cellulite

Treating skin can include delivering a beam of radiation to a target region of the skin to cause a zone of thermal injury including a lateral pattern of varying depths of thermal injury distributed along the target region. The lateral pattern includes at least one first sub-zone of a first depth of thermal injury laterally adjacent to at least one second sub-zone of a second depth of thermal injury. The first depth is greater than the second depth. The at least one first sub-zone of the first depth and the at least one second sub-zone of the second depth extend from a surface of the target region of the skin to form a substantially continuous surface thermal injury. The at least one first sub-zone of the first depth and the at least one second sub-zone of the second depth are substantially heated to at least a critical temperature.

Treatment of skin by spatial modulation of thermal heating

Reduction of pain through lower fluence rates and longer treatment times

Method of treating cellulite

Described is a device for driving a dermatological laser. The system includes a first diode, an inductor, a switch, and a photodetector. A first end of the inductor is coupled to an end of the first diode, and a second end of the inductor is coupled to a flashlamp. An electrical control of the switch is coupled to a control system, a first end of the switch is coupled to a power source, and a second end of the switch is coupled to the first end of the inductor and the end of the first diode. The photodetector is adapted to measure at least one of output energy or output power of a laser medium pumped by the flashlamp. The photodetector is in communication with the control system for modulating a flashlamp that drives current to maintain a predetermined value of the measured output energy or output power.

Voltage bucking circuit for driving flashlamp-pumped lasers for treating skin

Non-ablative skin resurfacing can include generating electromagnetic radiation having a wavelength of about 1920 nm to about 1950 nm and a fluence of about 3 J/cmto about 6 J/cm. The electromagnetic radiation is delivered to a target region of skin to cause thermal injury to the epidermis in the target region sufficient to elicit a healing response that produces a substantially improved skin condition without detachment of the epidermis (e.g., within 3 days of treatment).

Skin resurfacing at 1930 nm

The invention generally relates to treating diseased nails, and more particularly to treating diseased nails using radiation and/or another form of energy to substantially deactivate the source of the disease. A nail treatment can be performed by a medical professional without the use of a dying agent or an exogenous chromophore, and the treatment can be effective at eliminating the source of the disease without subjecting a patient to adverse side effects or causing substantial unwanted injury to surrounding tissue.

Method and apparatus for treating a diseased nail

A method for generating a long effective pulse duration output beam of laser radiation using a flashlamp-excited dye laser is described. A spaced series of excitation pulses is electronically generated using a pulse forming module. The series of excitation pulses are provided to a flashlamp-excited dye laser, which generates an output beam of laser radiation. The output beam is comprised of a series of spaced micropulses of laser radiation which, in combination, provide a long effective pulse duration.

Multipulse dye laser

A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region between 100 microns and 1.2 millimeters below a wrinkle in the skin, and thermally injuring collagen in the targeted dermal region. The beam of radiation has a wavelength of between 1.3 and 1.8 microns. The method may include cooling an area of the skin above the targeted dermal region while partially denaturing the collagen in the targeted dermal region. The method may also include cooling an area of the skin above the targeted dermal region prior to thermally injuring collagen in the targeted dermal region.

Method and apparatus for treating wrinkles in skin using radiation

A non-invasive apparatus and method for treating open angle glaucoma in a human eye comprises thermally ablating a targeted region of the trabecular meshwork of a human eye by irradiating the region with a beam of pulsed laser radiation. The beam of pulsed radiation has a wavelength between 350 and 1300 nanometers, energy of 10 to 500 millijoules per pulse, and pulse duration of 0.1 to 50 microseconds. The beam is non-invasively delivered gonioscopically through the cornea onto a targeted region of the trabecular meshwork. The targeted region of the trabecular meshwork is illuminated at a spot size of between 50 and 300 microns in diameter.

Apparatus and method for treating glaucoma using a gonioscopic laser trabecular ablation procedure

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Weston, MA, United States of America

James C Hsia