Abbott Laboratories Corporation

James Brooks Holland

Daniel Ambrose Dunnigan

Adolph Oscar Geiszler

Covers a compound selected from the group consisting of a member of the formula: ##STR1## wherein R.sub.1 is a radial selected from the group consisting of higher branched or straight chain alkyl and cycloalkyl radicals wherein said R.sub.1 radical contains at least six carbon atoms, R.sub.2 is a radical selected from the group consisting of hydrogen, loweralkyl and loweralkanol radicals, wherein said R.sub.2 radical contains 1 - 3 carbon atoms, and R.sub.3 is methoxy; and nontoxic pharmaceutically acceptable acid addition salts thereof. Also covers the use of said compound as a local anesthetic and pharmaceutical compositions comprising said above compounds as the active ingredient.

Aminotetralins and use in inducing anesthesia

Covers a compound selected from the group consisting of a member of the formula: ##STR1## where R.sub.1 is a radical selected from the group consisting of higher branched or straight chain alkyl and cycloalkyl radicals wherein said R.sub.1 radical contains at least six carbon atoms, R.sub.2 is a radical selected from the group consisting of hydrogen, loweralkyl and loweralkanol radicals, wherein said R.sub.2 radical contains 1-3 carbon atoms, and R.sub.3 is methoxy; and nontoxic pharmaceutically acceptable acid addition salts thereof. Also covers the use of said compound as a local anesthetic and pharmaceutical compositions comprising said above compounds as the active ingredient.

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Zion, IL, United States of America

James Brooks Holland