Omeros Corporation

Other

University of Leicester

James Brian Parent

Clark E Tedford

Thomas Dudler

Wayne Richard Gombotz

Anita Kavlie

Sergej Kiprijanov

Urs Beat Hagemann

Herald Reiersen

Hans-Wilhelm Schwaeble

Gregory A Demopulos

Bill Duddles

Carrie Spender

Teizo Fujita

Cordula Margaret Stover

Douglas M Davis

Caroline Lennox

Kyle Thalman

William Duddles

Brett Wargo

A bar tapping tool for use during a tap swing drill includes a plurality of bristles adjacent one another and extending horizontally so as to signal when the gymnast should begin her bodily shape change while keeping a safe distance from lower bar. The bar tapping tool has bristles of different lengths extending horizontally so that an athlete swinging on the upper bar can at first swing at a farther distance away from the lower bar and then later, when more experienced, swing at a closer distance away from the lower bar.

Bar tapping tool

In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2 inhibitory agent inhibits cellular injury associated with MASP-2-mediated alternative complement pathway activation, while leaving the classical (C1q-dependent) pathway component of the immune system intact. In another aspect, the invention provides compositions for inhibiting the effects of lectin-dependent complement activation, comprising a therapeutically effective amount of a MASP-2 inhibitory agent and a pharmaceutically acceptable carrier.

Methods for treating conditions associated with MASP-2 dependent complement activation

The present invention relates to anti-MASP-2 inhibitory antibodies and compositions comprising such antibodies for use in inhibiting the adverse effects of MASP-2 dependent complement activation.

Compositions for inhibiting MASP-2 dependent complement activation

An arm training band includes a strap having an elongate configuration and a pair of opposed loops coupled to opposite ends of the strap. The loops are specifically configured to fit or hook over a thumb of a user who is wearing the arm training band. The strap may be extended around the upper arm of the user proximate the user's elbow and the loops hooked over the user's thumb. Preferably, the user will wear an arm training band on each arm when training and practicing proper arm positioning when running.

Running training band

A parallettes apparatus is portable and configured to allow an athlete to exercise even when remote from a traditional gymnastics training facility. The portable parallettes apparatus includes a pair of base members and a bar member removably extending between respective base members. The pair of base members are hollow and configured to receive the bar during transport or storage.

Portable parallettes

A transition trampoline apparatus includes a transition trampoline bed having an elongate configuration that, when mounted on support legs, provides a track for a gymnast that is sufficiently bouncy to ease wear and tear on a gymnast's knees and ankles while not affecting her footwork while running and doing gymnastic maneuvers.

Transition trampoline bed

A miniature trampoline includes a frame having at least a pair of spaced apart upper frame members each having an upper front end and an upper rear end, respectively, the upper frame members being inclined toward the upper rear ends, respectively. A trampoline bed includes at least one planar surface and a pair of elongate side edges situated between the upper frame members and extending substantially between the upper rear ends and upper front ends of the pair of upper frame members, respectively. The trampoline includes a plurality of springs, each spring having a spring fastener coupled to a respective upper frame member and a bed fastener coupled to the trampoline bed proximate a side edge thereof, wherein the springs are spaced apart along the respective upper frame members, respectively, such that the trampoline bed is selectively held in tension between the upper frame members, respectively.

Vault shaped miniature trampoline

In one aspect, the invention provides methods of inhibiting the effects of MASP-2-dependent complement activation in a living subject. In one embodiment, the invention provides methods of treating a subject suffering from a complement mediated coagulation disorder, such as disseminated intravascular coagulation. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation. In some embodiments, the MASP-2 inhibitory agent inhibits cellular injury associated with MASP-2-mediated alternative complement pathway activation, while leaving the classical (C1q-dependent) pathway component of the immune system intact. In another aspect, the invention provides compositions for inhibiting the effects of lectin-dependent complement activation, comprising a therapeutically effective amount of a MASP-2 inhibitory agent and a pharmaceutically acceptable carrier.

Growing community of inventors

Bainbridge Island, WA, United States of America

James Brian Parent