Mayo Foundation for Medical Education and Research

Renew Group Pte. Ltd.

General Electric Company

Echometrics Cardiologists, Pc

James Bernard Seward

Abdul Jamil Tajik

Charles J Bruce

Richard A Robb

Douglas L Packer

Bijoy K Khandheria

Bruce M Cameron

Trudy J Wellik

William H Hansen

James A Koerner

Gregory Gilman

A medical general intelligence computer system and computer-implemented methods analyze morpho-physiological numbers for determining a risk of an emergent disease state, determining an emergent disease state, predicting a pre-emergent disease state, determining a pre-emergent disease state, and/or predicting a risk of a pre-emergent disease state.

Artificial general intelligence method for determining a disease state using a general graph and an individualized graph

Artificial general intelligence system and method for medicine that determines a pre-emergent disease state of a patient based on mapping a topological module

Determining disease state of a patient by mapping a topological module representing the disease, and using a weighted average of node data

Artificial general intelligence system/medical reasoning system (MRS) for determining a disease state using graphs

A knowledgebase comprising a plurality of feature-sets is created using complexity science. The knowledgebase is accessible through a network to a computer, a system, and a computer program code that receives and analyzes medical data to determine the existence of a disease state. The medical data is input and correlated to features within the knowledgebase to identify feature-sets, each feature-set indicating a particular medical condition. After one or more feature-sets have been selected, associative algorithms consider the magnitudes or values of the medical data and, with the values of features in the feature-sets, assess the risk burden of the medical condition associated with the feature-set. An output is generated that may include diagnoses of one or more medical conditions, the risk burden of the medical condition(s), possible treatment options and prevention techniques.

Automated management of medical data using expert knowledge and applied complexity science for risk assessment and diagnoses

A multifunctional information management system that integrates a plurality of modules, each of the modules being interfaced via a relational database. The integrated system manages a large volume of business, data, and image information and is capable of being accessed/organized via the Internet. One embodiment of the multifunctional information management system is an ultrasound laboratory information management system (ULIMS) for a medical ultrasound imaging and hemodynamic laboratory, e.g., an echocardiographic or comparable medical laboratory environment, incorporating a multifunctional management system. The ULIMS includes: 1) Scheduling and Workflow Modules; 2) Patient Information and Demographics Modules; 3) Billing Modules; 4) Procedure Information and Referral Diagnosis Modules; and 5) Measurement, Templates and Calculations Modules; 6) Final Impressions and Interpretation Modules; 7) Procedure Report Modules; 8) Serial Studies Module; 9) Research Protocols Module; 10) User Interface and Services Modules; 11) Web Based Modules; 12) Unique Reports Modules; 13) Database Modules; 14) Systems Administration Modules; 15) Security, Privacy and User Configuration Modules; 16) Image Modules; 17) Systems and Technical Support Modules; and 18) Knowledge Base Modules.

Ultrasound laboratory information management system and method

An underfluid ultrasound imaging catheter system includes a catheter having a distal end inserted into an underfluid structure, an ultrasonic transducer array mounted proximate the distal end of the catheter wherein the array has a row of individual transducer crystals, a lens mounted on the array for defocusing ultrasound beams in a direction perpendicular to an axis of the array so as to provide a volumetric field of view within which the underfluid features are imaged. Alternatively, the single row of transducer crystals is replaced by multiple rows of transducer crystals so as to provide a volumetric field of view. This imaging catheter system helps an operator see 3-dimensional images of an underfluid environment, such as the 3-dimensional images of fluid-filled cavities of heart, blood vessel, urinary bladder, etc. Features in such wide volumetric field of view can be imaged, measured, or intervened by an underfluid therapeutic device with an aid of the real-time image.

Volumetric image ultrasound transducer underfluid catheter system

A miniaturized ultrasound transducer (e.g. less than 4 mm&#xd7;4 mm&#xd7;10 mm) is provided and is operable in small spaces, such as within a surgical field and placed upon, within, attached to, embedded within, etc. structures, organs or devices. The ultrasound transducer may be mounted onto or incorporated into a holding device to foster easily manipulation of the small transducer. The ultrasound transducer communicates with a processing unit via an electrical wire or cable or wirelessly.

Small ultrasound transducers

A parametric imaging ultrasound catheter apparatus is capable of obtaining parametric images of the surrounding insonated environment. Parametric imaging is defined as the imaging of quantifiable &ldquo;parameters&rdquo; which of visible two-, three-, fourth-dimensional or non-visible higher-dimensional temporal physiologic events. Visible motion is a fourth-dimensional event and includes surrogate features of cardiac muscle contraction, wall motion, valve leaflet motion, etc. Non-visible motion is a higher-dimensional event and includes slow non-visible events (i.e., remodeling, transformation, aging, healing, etc.) or fast non-visible events (i.e., heat, electricity, strain, compliance, perfusion, etc.). An ultrasound catheter with parametric imaging capability can obtain dynamic digital or digitized information from the surrounding environment and display information features or quanta as a static or dynamic geometric figures from which discrete or gross quantifiable information can be obtained. A quantifiable geometric image or parametric information may have little resemblance or dependence on the fundamental ultrasound image. Parametric ultrasound information may be used as a surrogate for common visible or non-visible events such as electrical depolarization of the heart, perfusion, myocardial injury, etc.

Parametric imaging ultrasound catheter

An apparatus and method for holding and manipulating a miniaturized ultrasound transducer includes a flexible member, a retaining member, and a control member. The miniaturized ultrasound transducer is mounted on the flexible member proximate a distal end of the flexible member. The retaining member retains the flexible member proximate the distal end of the flexible member. The control member is coupled to the retaining member and is operable to move the retained flexible member and ultrasound transducer to optimize ultrasound visualization.

Apparatus and method of holding and manipulating small ultrasound transducers

A self-contained ultrasound catheter device capable of delivering diagnostic and therapeutic tools in a field of ultrasound includes a rotatable multiplane sector phased array imaging ultrasound transducer used for the visualization of under fluid structures and/or diagnostic and therapeutic events. The multiplane sector phased array is rotatable around an axis of an ultrasound beam to obtain sequential imaging planes in a continuous or interrupted sweep up to 360 degrees. The transducer being a multiplane transducer allows more versatile visualization of underfluid structures and/or events. The sequential acquisition of tomographic images is suitable for 3-dimensional image reconstruction.

Growing community of inventors

Rochester, MN, United States of America

James Bernard Seward