Glaxo Group Limited

Sanofi

Sanofi-a Ventis Deutschland Gmbh

Hewlett-packard Development Company, L.p.

Roche Diagnostics Gmbh

Dovia International Limited

James Anthony West

Mark Digby Teucher

Gregor John McLennan Anderson

James Robert Coop

Stephen Francis Gilmore

Stefan Blancke

Andrew Michael Kelly

Daniel David Higgins

Ralph Donald Quentin Collings

Paul Kenneth Rand

Allen John Pearson

Matthew Spencer Collins

David Vincent Elliman

Richard David Lintern

Michael Jugl

Matthew Meredith Jones

Anthony Paul Morris

Axel Teucher

Paul Graham Hayton

William Geoffrey Arthur Marsh

Gary Thomas Crosby

Sophie Louise Sladen

Samuel Steel

Craig Ian Wightman

Marc Holtwick

Stephen James Harvey

Andreas Bode

Philip William Farr

Daniel Thomas De Sausmarez Lintell

Thomas Jaeck

Jack Carroll

Andrew Mark Fernihough

Mark Dillon

Philip Turner

Christopher Thomas Elsworthy

Alexa Nagel

Christopher Kilbane

Andrew Roderick Taylor

Denny Lustosa Horn

Silke Vogt

Bernd Eisenbarth

Maria Van Gelder

Wolfgang Marx

Joseph Paul Marino

Laura Stein

Timothy Robin Quigg

Gregor John Mclennan Anderson

A drive train for a wind-up injection device, comprises a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle coupled with a button, a rotationally drivable expelling mechanism, and a clutch element coupled with the torsional energy storage via the rotatable element and comprising a ratchet for maintaining the rotatable element at one of a number of discrete angular positions, wherein via the rotatable element, the clutch element is adapted to transmit a torque from the user handle to the torsional energy storage or from the torsional energy storage to the expelling mechanism, and wherein the ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage, and wherein the drive train is adapted to dampen torque peaks by a flexible impact portion in the area of the clutch element.

Drive train for dial of a torsion-spring assisted wind-up injection device

A button for a drug delivery device with a reduced operating loudness includes a plate-like button body forming a touch surface, wherein the plate-like button body is coupled by an axial supporting member to a noise-generating interface of the drug delivery device and movable into a longitudinal direction of the drug delivery device, wherein the plate-like button body includes a material composite with at least one first component consisting of a first material and at least one second component consisting of a second material different from the first material, wherein the at least one first component and the at least one second component are coupled via at least one coupling plane that is at least sectionwise slanted or perpendicular to the longitudinal direction. Further, the disclosure describes a button assembly for a drug delivery device which is shock resistant.

Button and button assembly for a drug delivery device

A drive train for a wind-up injection device is described. The drive train includes a torsional energy storage adapted to be loaded or unloaded by a rotatable element, a rotatable user handle, a rotationally driveable expelling mechanism adapted to expel the liquid drug, and a clutch element coupled with the torsional energy storage via the rotatable element and including a ratchet for maintaining the rotatable element at one of a number of discrete angular positions against the torque of the torsional energy storage. The clutch element is adapted to transmit the torque from the user handle to the torsional energy storage, or alternatively from the torsional energy storage to the expelling mechanism. The ratchet is switchable from one position to an adjacent position by a torque transmitted from the user handle to the torsional energy storage. The drive train is adapted to dampen torque peaks visco-elastically and/or visco-frictionally.

A drive mechanism for a drug delivery device with a reduced operating loudness includes a dose selector, a housing, and a ratchet with a gear element comprising a plurality of gear teeth connected with the dose selector and a pawl element rotationally constrained to the housing comprising at least one pawl tooth. The at least one pawl tooth engages with the gear teeth and is located opposite to the gear teeth. One of the gear element and the pawl element moves forth and back relative to the other element of the gear and pawl elements along a first direction for de-engagement and re-engagement of the opposite gear teeth and at least one pawl tooth when the gear element rotates relative to the housing during dose setting using the dose selector. The pawl element and/or gear element comprises a noise reduction characteristic at a surface which dampens the noise produced.

Drive mechanism with noise reduction

A system comprises a first member, a second member, and a third member, wherein the first and second members are rotatable relative to the third member, wherein the first and second members are coupled to one another by a dead-angle follower coupling, wherein the dead-angle follower coupling is configured such that the first and second members are rotatable relative to one another, wherein the second and third members are rotationally coupled to one another by a switchable coupling mechanism, wherein the switchable coupling mechanism is switchable between two different states, a locked state and a non-locked state, wherein the maximum torque transferable between the second and third members via the switchable coupling mechanism in the locked state is greater than in the non-locked state, wherein the switchable coupling mechanism is in the locked state when the first member is in a locking position relative to the second member.

Ratchet systems for drug delivery devices

The disclosure is directed to a drug delivery device comprising a housing retaining a primary drug delivery assembly and a secondary drug delivery assembly. The secondary drug delivery assembly comprises a secondary dose setting mechanism with a biasing member adapted to reset the secondary dose setting mechanism in a resetting movement. An actuator is movable relative to the housing and comprises a first engagement section configured to engage a second engagement section provided by an actuation collar such that an actuation movement of the actuator is transferred to the actuation collar. A setting element is movable between a first position and a second position and is connected to the secondary dose setting mechanism such that during the resetting movement of the secondary dose setting mechanism, the setting element is moved from the second position into the first position.

Drug delivery device for the delivery of two medicaments

Drug delivery device comprising a housing retaining a primary drug delivery assembly for the delivery of a primary medicament with a primary dose setting member configured to rotate in a helical movement to set a dose of the primary medicament and a secondary drug delivery assembly for the delivery of a secondary medicament. A dose dial is movable between a first position and a second position in axial direction and is rotationally constrained with respect to the housing when moved from the first position into the second position and is rotationally constrained to the primary dose setting member in the second position for setting a dose of the primary medicament. A secondary drive sleeve of the secondary drug delivery assembly serves for dispense of the secondary medicament. The dose dial and the secondary drive sleeve can be coupled for dose setting.

Drug delivery device

There is provided a drug dispenser device comprising a housing; extending from the housing, an outlet for insertion into a body cavity of a patient; provided to the housing and moveable with respect thereto, a drug discharge device having a longitudinal axis and comprising a container for storing a drug formulation to be dispensed, a discharge mechanism and a discharge channel from the container for discharge of the drug formulation to the outlet; connecting to the drug discharge device, a container collar; connecting to the container collar and moveable with respect thereto along the longitudinal axis of the drug discharge device, a transfer element, the transfer element including an actuating portion; provided to the housing, at least one finger operable member moveable to apply a force to the actuating portion of the transfer element to move the transfer element along the longitudinal axis in a first direction; linking the container collar with the transfer element, a biasing mechanism to store biasing energy on moving the transfer element along the longitudinal axis in the first direction; and provided to the container collar, a pre-load mechanism to prevent transfer of the biasing energy to the container collar to move the drug discharge device along the longitudinal axis in the first direction to actuate the discharge mechanism until a pre-determined threshold force is overcome.

Drug dispenser using a catapult arrangement

This invention relates to a mechanism for use in a device that comprises a system for collecting dirt and debris from a variety of floor and upholstery surfaces. In particular the mechanism lifts and directs unwanted debris particles to a waste reservoir for the purpose of cleaning and grooming floor surfaces. The debris collection mechanism can be, but is not limited to its use in a handle operated cordless motorized floor sweeper to collect and gather unwanted debris and dust. The device includes a head unit that incorporates two easily removable elongate cylindrical rotating cleaning bars that are driven such that they contra rotate, and are positioned close to one another at the forward region of the head unit. A removable debris reservoir, removable rechargeable power source and handle incorporating a device operation switch are also included.

Surface debris removal apparatus

A fault indicator for a strip advancement mechanism comprising a base that defines a fault sensing portion of a path for at least a component of a strip, an element for bearing against a strip, or a component of the strip, while it passes through the fault sensing portion of the path, wherein the element is adapted to move from that bearing or non-fault position, to a fault indicating position in the event of the strip or the component of the strip ceasing to pass through the fault sensing portion of the path.

Fault indicator

Mouthpiece

Inhaler

A tape cartridge includes a housing and a tape reel that is rotatable about an axis of rotation. The tape reel is adapted to cooperably engage a reel drive member of a data transfer apparatus that, in use, applies a drive torque to the tape reel to rotate the tape reel about the axis of rotation. The cooperable engagement of the tape reel and reel drive member is such as to secure the tape reel to the reel drive member to at least substantially prevent tipping of the tape reel with respect to the reel drive member.

Data transfer apparatus for use with tape cartridges having a helical cammed surface and tape cartridges having cammed surface for use with such data transfer apparatus

Growing community of inventors

Bristol, United Kingdom

James Anthony West