Becton Dickinson and Company Limited

Sanofi-A Ventis Deutschland Gmbh

Sanofi

Other

James Alexander Senior

Malcolm Stanley Boyd

Oliver Charles Gazeley

David Aubrey Plumptre

Gareth James Lewis

Richard James Vincent Avery

Michael Vincent Quinn

James Alexander Davies

Mohammed Yassir Mahdi

Robert F Veasey

Christopher Nigel Langley

Elliot Baxter

Jamie Anthony Salter

Javier Eduardo Nadal

Harry Robert Lester

Michael Harms

Steffen Raab

Udo Stauder

Thomas Khong

Richard James Avery

The present disclosure refers to a housing element for a drug delivery device. The housing element comprises longitudinal axis and defines an interior space for receiving components of a drive mechanism of the drug delivery device and at least a portion of a cartridge of the drug delivery device. The housing element comprises an engagement feature for axially constraining the housing element to a cartridge holder of the drug delivery device. In order to constrain the cartridge in the housing element, it further comprises at least one crush web protruding radially inwards into the interior space. The at least one crush web is angled relative to the longitudinal axis of the housing element by at least 3° such that when the cartridge is introduced into the interior space the at least one crush web folds radially outwards.

Housing element and drug delivery device herewith

A drug delivery device comprising a housing with an opening, a piston rod having a proximal end and a distal end, and a bearing. The piston rod is adapted to engage the opening for guiding the piston rod during a movement of the piston rod relative to the housing. The piston rod also includes a first attachment element located at the distal end. The bearing has a second attachment element for rotatable attachment of the bearing at the distal end of the piston rod. The first attachment element and/or the second attachment element is elastically deformable in a radial direction for snap engagement of the piston rod and the bearing. The opening is adapted to receive the first attachment element and the second attachment element if attached to each other but preventing disengagement of the first attachment element and the second attachment element if received in the opening.

Drug delivery device and assembly method for a drug delivery device

A needle actuator assembly for a drug delivery system includes a needle actuator body having a guide surface, a needle shuttle having a cam surface, with the needle shuttle moveable along a vertical axis between a first position and a second position. The needle shuttle is configured to move between the first and second position through engagement between the guide surface of the needle actuator body and the cam surface of the needle shuttle. The assembly further including a needle received by the needle shuttle.

Needle actuator assembly for drug delivery system

A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.

Spacer assembly for drug delivery device

A drug delivery system for injecting a medicament includes a housing, a container configured to receive a medicament including a stopper configured to move within the container and a closure, a needle in fluid communication with the container, a spacer configured to be engaged with the stopper, a first plunger, a first spring configured to bias the first plunger in an axial direction, second plunger disposed about the first plunger, a second spring configured to bias the second plunger in an axial direction. The first plunger is configured to move the spacer and the container relative to the housing via the first spring to establish fluid communication between the container and the patient needle, and the second plunger is configured to move the spacer and the stopper relative to the container via the second spring.

Drive assembly and spacer for drug delivery system

A drug delivery system for injecting a medicament is provided. The system includes a container configured to receive a medicament; a drive assembly which, upon actuation, is configured to expel the medicament from the container; a needle for injecting the medicament to a patient; a fluid path assembly comprising a tube in fluid communication with the container and the needle for conducting fluid from the container to the needle; and a tube crimping arrangement configured to engage the tube to block fluid flow through the tube. The drive assembly causes the tube crimping arrangement to engage the tube after a dose of the medicament has been delivered to the patient through the needle.

Tube crimping arrangement for drug delivery device

A drive mechanism for an injection device for setting and dispensing of a dose of a medicament includes an inner body fixable inside a housing of the injection device, the inner body including an elongated shaft extending in an axial direction. The elongated shaft includes an outer thread and a blocking structure on an outer circumference. The drive mechanism includes a tubular-shaped display member having an inner thread engaged with the outer thread of the inner body, a dose member axially displaceable between a dose setting position and a dose dispensing position relative to the inner body, and a blocking sleeve axially fixed to the dose member, rotationally fixed to the display member and including at least one blocking element to axially engage with the blocking structure to block an axial displacement of the dose member from the dose setting position towards the dose dispensing position.

Drive mechanism for an injection device

A drive mechanism for an injection device includes an inner body fixable inside a housing. An elongated shaft of the inner body extends in an axial direction. The shaft includes an outer thread and a blocking structure on an outer circumference. A tubular-shaped display member has an inner thread engaged with the outer thread of the inner body (). A dose member is axially displaceable between a dose setting position and a dose dispensing position relative to the display member. The dose member includes at least one blocking element displaceable, pivotable or bendable in radial direction between a blocking position and a release position and engageable with the blocking structure for inducing a radial displacement of the blocking element. In the blocking position, the blocking element axially abuts with the blocking structure and with the display member to block an axial displacement of the dose member from the dose setting position towards the dose dispensing position.

The present disclosure relates to a drive mechanism for an injection device. The mechanism includes an inner body fixable inside a housing of the injection device and including an elongated shaft extending in an axial direction. The shaft includes an outer thread and a blocking structure on an outer circumference. A tubular-shaped display member has an inner thread engaged with the outer thread of the inner body. A dose member is axially displaceable relative to the inner body or the display member between a dose setting position and a dose dispensing position. A blocking ring is axially engageable with the dose member, rotationally fixed to the display member and includes a blocking element to axially engage with the blocking structure for blocking an axial displacement of the dose member from the dose setting position towards the dose dispensing position.

The present invention relates to a drug delivery device () comprising a dose button (). Furthermore it relates to a method for manufacturing a dose button () by using a cutting-off process. The aim of the present invention is to minimize the risk of using a drug delivery device () containing a wrong drug. By means of tactile features, a drug delivery device () is distinguishable from another drug delivery device () containing another type of drug. This tactile feature is manufactured by using a dose button () out of metal which is milled or lathed.

Growing community of inventors

Warwick, United Kingdom

James Alexander Senior