The United States of America, As Represented by the Secretary, Department of Health and Human Services

James A Comer

Thomas G Ksiazek

Pierre E Rollin

Stuart T Nichol

Larry J Anderson

Anthony Sanchez

Raymond Campagnoli

M Steven Oberste

Cara Carthel Burns

William Allan Nix

Paul A Rota

Dean D Erdman

Suxiang Tong

Mark A Pallansch

Cynthia Goldsmith

William J Bellini

Jonathan S Towner

Stephan S Monroe

Teresa C T Peret

Sherif R Zaki

Joseph P Icenogle

Charles D Humphrey

Shannon L Emery

Qi Chen

Richard F Meyer

Jeanette Guarner

Christopher D Paddock

Byron T Cook

Wun-Ju Shieh

Michael D Bowen

Compositions and methods including and related to the Ebola Bundibugyo virus (EboBun) are provided. Compositions are provided that are operable as immunogens to elicit and immune response or protection from EboBun challenge in a subject such as a primate. Inventive methods are directed to detection and treatment of EboBun infection.

Human ebola virus species and compositions and methods thereof

Human Ebola virus species and compositions and methods thereof

Disclosed herein is a newly isolated human coronavirus (SARS-CoV), the causative agent of severe acute respiratory syndrome (SARS). Also provided are the nucleic acid sequence of the SARS-CoV genome and the amino acid sequences of the SARS-CoV open reading frames, as well as methods of using these molecules to detect a SARS-CoV and detect infections therewith. Immune stimulatory compositions are also provided, along with methods of their use.

Coronavirus isolated from humans

Growing community of inventors

Decatur, GA, United States of America

James A Comer