Micromass UK Limited

Jakub Ujma

Kevin Giles

Jason Lee Wildgoose

Martin Raymond Green

Steven Derek Pringle

Keith George Richardson

Daniel James Kenny

David John Langridge

James Paul Harrison

Bharat Chande

Sandra Richardson

Nick Tomczyk

Graham Scambler

Martin Palmer

Eleanor Riches

A method of selecting ions comprises selecting ions corresponding to a target ion of interest by separating analyte ions according to their ion mobility, isolating first ions of the analyte ions, separating the first ions according to their ion mobility, and isolating second ions of the first ions. Preferably, the separation is accomplished by using a cyclic or closed-loop separator.

Method of selecting ions by ion mobility separation and isolation of ions

An ion guide or ion trap that comprises a plurality of electrodes () is disclosed. The ion guide or ion trap includes a detector () that can detect light or particles () emitted from the ion guide or ion trap due to electrical breakdown, and a control circuit () that can control the ion guide or ion trap in response to the detector () detecting light or particles () emitted from the ion guide or ion trap.

Ion guide

A method of identifying and/or characterising ions comprises separating analyte ions according to a first physico-chemical property (ion-mobility), selecting first ions of the analyte ions, and activating, fragmenting or reacting the first ions to produce first product ions, separating the first product ions according to the first physico-chemical property, and determining a pattern of the first product ions. The first ions are identified and/or characterised using the pattern of the first product ions.

Method of characterising molecules by ion-mobility spectrometry

A method of controlling the operation of an ion mobility separation device is disclosed. The method comprises displaying to a user via a user interface a pool of modes of operation of the ion mobility separation device, wherein each one of the modes is selectable by the user for inclusion in an experiment, and the modes are displayed in a first areaof the user interface. The method comprises receiving, via the user interface, an indication from the user of a selection of one or more instance of each one of a plurality of the modes from the pool to be included in an experiment, and an indication from the user of a set of one or more parameters for controlling the ion mobility separation device in respect of one or more selected instances of a mode. The selected instances of modes are displayed in a sequence in a second areaof the user interface. The operation of the ion mobility separation device is controlled in accordance with the received indications.

User interface for ion mobility separation device

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Manchester, United Kingdom

Jakub Ujma