Civitas Therapeutics, Inc.

Dose One, LLC

Children's Medical Center Corporation

Klean Kanteen, Inc.

Spinal Stabilization Technologies, LLC

Iinjec Technologies Inc.

One Dose, LLC

Jake P Ganem

Charles F Ganem

Kevin Stapleton

Brian Noble

Scott E Ganem

Colleen Ellwanger

Chuck Ganem

Sean Plunkett

Scott Ganem

Jeffrey Cerier

Andrew L Cote, Sr

James M Osgood

Mark A Novotny

W Loren Francis

Anthony Maiorano

Cory R A Hallam

Catherine Reisenburg Molson

Alexandra Molson

The present disclosure includes devices, apparatuses, kits, and methods for replacing a nucleus pulposus of an intervertebral disc with an implantable nuclear prosthesis filled with a curable silicone material in situ. Configurations of the present spinal implant devices include a flexible body defining an outer fillable enclosure that defines an outer chamber, an inner fillable enclosure that defines an inner chamber, and a proximal plug configured to be coupled to the inner fillable enclosure.

Implantable nuclear prosthesis, kits, and related methods

A gasket for creating a fluid seal in a medical device includes a flexible base, a flexible hollow body, and a multi-leaflet valve. The flexible hollow body extends along an axis from a hole defined in the flexible base. The flexible hollow body is configured to have a relaxed state in which a cross section of the flexible hollow body has a first shape and a compressed state in which the cross section of the flexible hollow body has a second shape. The multi-leaflet valve is disposed in the flexible hollow body. The compressed state causes the multi-leaflet valve to close to increase (a) a first threshold force or a first threshold pressure differential needed to open the multi-leaflet valve in a distal direction and (b) a second threshold force or a second threshold pressure differential needed to open the multi-leaflet valve in a proximal direction.

Gasket with multi-leaflet valve for surgical port apparatus

A fluid delivery injector comprises a syringe defining a barrel; a plunger and a hollow needle provided within the barrel adapted for linear movement parallel to a longitudinal axis with a distal tip of the needle contained within the syringe. A fluid retention reservoir is defined at least in the barrel and is in fluid communication with the needle when pressure is applied to the fluid in the reservoir and to the plunger for moving the needle out of the barrel. A spring may be provided for retracting the needle when pressure is released from the plunger.

Fluid delivery device and method

An improved inhalation device is provided for facilitating inhalation by a patient of powder medicaments contained in a receptacle. The inhalation device includes a staple assembly comprising a plunger and staple that are securely and robustly coupled to one another. Embodiments of the inhalation device have a cap that prevents or reduces the amount of dust and grime entering into the device. The cap is additionally configured to prevent or reduce inadvertent and unintentional operation of the device. The body portion and first casing portion of certain embodiments of the inhalation device are sealably coupled, restricting or reducing undesirable flow pathways that have an adverse effect on the operation of the device.

Powder inhaler devices

A container lid assembly configured to be used with and seal a container body is provided. The container lid assembly includes a container lid including a plug member extending downwardly and a gasket-retaining portion adjacent to and at least partially surrounding the plug member, where an outer surface of the plug member defines at least part of the gasket-retaining portion. The container lid assembly further includes a sealing gasket retained on the gasket-retaining portion and configured to provide a seal between the outer surface of the plug member and an interior wall of the container body, where the sealing gasket includes a pull tab that (i) extends away from a sealing portion of the sealing gasket; and (ii) extends downward away from the gasket-retaining portion of the container lid.

Container and container lid assembly with a removable sealing gasket

Indicator for an inhaler

Inhaler grip

A medication inhaler comprising an inhaler body, having a medication container chamber for receiving a medication container and an air passage coupling the medication container chamber with exterior air, and a mouthpiece axially engageable with the inhaler body. The mouthpiece has a mouthpiece chamber and a medication delivery needle communicating with the mouthpiece chamber. The needle extends toward the medication container chamber and has an opening for supplying exterior air and medication from an interior cavity of the medication container, accommodated within the medication container chamber, through the needle and to mouthpiece chamber. In the first position, the mouthpiece engages with the inhaler body with such that the needle is spaced from the medication container, and, in the second position, the needle axially traverses the medication container so that the opening in the needle communicates with the air passage and the interior cavity of the medication container to deliver the medication to the patient. The medication inhaler also includes an air bypass which bypasses the needle and supplies supplemental exterior air to the mouthpiece chamber to increase airflow through the medication inhaler.

Medication inhaler

A medication inhaler for concurrently delivering multiple doses of medications including an inhaler body having a medication container chamber for receiving a plurality of medication containers and at least one air passage connecting the medication container chamber with external air, a mouthpiece axially engageable with the inhaler body and having a mouthpiece chamber for communication with a patient's respiratory system, and a hollow medication delivery needle communicating with the mouthpiece chamber. A medication delivery needle penetrates the medication containers when the inhaler is actuated and has at least one opening for passing exterior air and medication from interior spaces of the medication containers and through the needle to mouthpiece.

Medication inhaler for dispensing multiple capsules

A medication inhaler having an inhaler body with a medication container chamber for receiving a medication container and at least one air passage connecting the medication container chamber with external air and a mouthpiece axially engageable with the inhaler body and having a mouthpiece chamber for communication with a patient's respiratory system and a hollow medication delivery needle communicating with the mouthpiece chamber. The medication delivery needle extends toward the medication container chamber and has at least one opening for passing exterior air and medication from an interior space of a medication container in the medication container chamber through the needle and to mouthpiece chamber. The mouthpiece engages with the inhaler body in a first position wherein the needle extends into the medication container chamber short of the medication container in the medication container chamber and in a second position wherein the needle axially traverses the medication container so that the at least one opening in the needle communicates with the at least one air passage and the interior space of the medication container in the medication container chamber.

Growing community of inventors

Cape Neddick, ME, United States of America

Jake P Ganem