Ucb Biopharma Sprl

B. Braun Medical Inc.

Jake A Cowperthwaite

Alex K Flamm

Eric Freitag

Daniel Formosa

Martin John McLoughlin

Brian Lee Lipford

Kevin Richard Lozeau

Agnete Enga

Ilario Melzi

Darrell P Morgan

Michael Schumann

Michael James David Heald

Heather Martin

Joel Martin Bartholomew

Mariano Mumpower

Keith Lipford

Benjamin R Lane

Mike Janders

Aaron Samuel Pearl

Karl Konrad, Jr

Edwin Leighton Burnard

Chet B Larrow

Michael Y Brown

Dave E Hershey

Conrad Laskowski

Jeremy C Savage

Jamie Kendall

Jonathan Bodnar

John Bodnar

Eric Freitags

Darell P Morgan

Erwin Burnard

Martin John Mcloughlin

Edwin Burnard

Joel Bartholomew

Karl Konrad

An exemplary compounding system and method can include two pump heads for simultaneously drawing two different fluids from at least two separate input containers such that the at least two different fluids are mixed and distributed to an output container. The system can include a manifold that maintains separation of certain of the different fluids until after passing by a first pump and a second pump and/or additional pumps. A junction can be placed in the fluid line downstream of the first and second pumps and/or additional pumps such that all or some of the fluids are mixed prior to output to the output container. The method of using the system can include incorporating software that selects various fluids at certain times and sequences to ensure optimum efficiency and safety for the system, and can continue compounding actions even when an input supply container runs out or otherwise fails to supply a particular fluid/material. The method of use also includes connection of a transfer set to a housing in a manner that further ensures optimum efficiency and safety.

Compounding device, system, kit, software, and method

Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The cassette unit housing cavity is arranged for receipt of a syringe. The syringe has a barrel for containing a volume of a liquid drug formulation, the barrel defining a flange at the rear end thereof and a forward shoulder at the forward end thereof; a hollow needle at a front end of the barrel, the hollow needle defining a needle tip; and a plunger that is axially movable within the barrel. The cassette unit includes, in contact with the plunger and axially movable within the barrel, a plunger slaving part arranged such that when a drive load is applied to a rear drive-receiving face thereof the drive load is evenly transmitted to the plunger.

Auto-injector

Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The housing cavity is arranged for receipt of a syringe suitable for delivery of a drug to a patient. The syringe has a barrel for containing a volume of a liquid drug formulation, the barrel defining a flange at the rear end thereof and a forward shoulder at the forward end thereof. The cassette unit includes one or more shoulder support features for supporting the forward shoulder of the syringe. In use, the one or more shoulder support features act to direct a major part of an applied load path to travel through the shoulder at the forward end of the syringe and lesser load to pass through the flange at the rear end thereof.

Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The housing cavity is arranged for receipt of a syringe for injected delivery of a drug to a patient. The cassette unit includes a removable cap that in a capping position fits over and thereby acts to close off the needle projection aperture; and connecting to the removable cap, a needle cover defining a needle sheath for sheathing the needle tip of the syringe. The removable cap is provided with one or more first engagement features arranged for selectively engaging one or more second engagement features of the cassette unit housing when the removable cap is in the capping position to thereby restrict/prevent rotation of the removable cap and needle cover relative to the housing.

Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The cassette unit housing cavity is arranged for receipt of a syringe suitable for use in the injected delivery of drug to a patient. The cassette unit includes a needle cover defining a needle sheath. The removable cap is provided with a connector defining one or more needle cover gripping elements for gripping the needle cover. The connector defines a central hub and the one or more needle gripper elements attach to the central hub and in spaced arrangement relative to each other. The connector locates within the removable cap such that the central hub of the connector is in spaced relationship with a far end wall or surface of the cap interior.

There is provided a cassette unit that is suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The cassette unit housing cavity is arranged for receipt of a syringe that is suitable for use in the injected delivery of drug to a patient. The cassette unit includes a removable cap that in a capping position fits over and thereby, acts such as to close off, the needle projection aperture. The cassette unit includes a cap lock feature movable from a first cap locking position in which it prevents removal of the removable cap from the capping position with the cassette unit to a second cap non-locking position in which it no longer prevents such cap removal.

There is provided a cassette unit that is suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The cassette unit housing cavity is arranged for receipt of a syringe that is suitable for use in the injected delivery of drug to a patient. The cassette unit includes a removable cap that fits over and thereby, acts such as to close off, the needle projection aperture; and connecting to the removable cap, a needle cover defining a needle sheath for sheathing of the needle tip of the syringe. The removable cap is provided with a finger-grip feature that is sized and shaped for gripping by the finger of a user to allow for removal of the removable cap and needle cover from the cassette unit housing.

Provided is a cassette unit suitable for use with an auto-injector having an electrically powered drive unit. The cassette unit has a housing defining a cassette unit housing cavity and a needle projection aperture. The housing cavity is arranged for receipt of a syringe suitable for use in the injected delivery of drug to a patient. The syringe has a barrel for containing a volume of a liquid drug formulation, the barrel defining an end flange at the rear end thereof and a forward shoulder at the forward end thereof. The cassette unit includes a sleeve form adapter arranged for receipt by the syringe barrel and to fit at least partly over the end flange of the syringe barrel. Accommodation of different syringe sizes within the same cassette unit geometry is achievable by selecting a sleeve form adapter tailored to the particular sizing of the barrel of each different syringe.

There is provided an auto-injector for a syringe that is suitable for use in the injected delivery of drug to a patient. The auto-injector comprises a cassette unit arranged for receipt of a syringe provided with a needle cover and removable cap. The auto-injector also comprises a drive unit arranged for docking receipt of the cassette unit at a docking position and a drive arrangement. The drive unit is provided with a timer that starts a time count on removal of the removable cap and needle cover from the cassette unit.

Provided is an auto-injector for a syringe suitable for the injected delivery of drug to a patient. The auto-injector comprises a cassette unit arranged for receipt of a syringe. The cassette unit and/or syringe is movable from a rest position, in which the syringe needle tip is within the drive unit housing to a use position, in which the needle tip protrudes from a needle delivery aperture thereof. The auto-injector comprises a drive unit arranged for docking receipt of the cassette unit at a docking position and a drive arrangement. The drive unit is arranged for initial receipt of the cassette unit at an intermediate pre-docking position and for subsequent transport of the cassette unit to the docking position. In embodiments, the drive unit is arranged such that transport of the cassette unit to the docking position is permitted only following verification of an identifier at the intermediate pre-docking position.

Growing community of inventors

Baltimore, MD, United States of America

Jake A Cowperthwaite