Merck Sharp + Dohme Corp.

Jaiqiang Cai

Yusheng Xiong

Clare London

Andrew John Cooke

Scott B Hoyt

Emma Louise Carswell

Paul David Ratcliffe

D Jonathan Bennett

Bheemashankar A Kulkarni

Swapan Kumar Samanta

Min K Park

John K MacLean

Jerry Andrew Taylor

John MacLean

Amjad Ali

Brent Whitehead

Michael Lo

John Maclean

Emma Carswell

Andrew Cooke

D Jonathan Bennet

Brent White-Head

This invention relates to pyrazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.

Pyrazolopyridyl compounds as aldosterone synthase inhibitors

This invention relates to triazolopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.

Triazolopyridyl compounds as aldosterone synthase inhibitors

This invention relates to imidazopyridyl compounds of the structural formula: or their pharmaceutically acceptable salts, wherein the variable are defined herein. The inventive compounds selectively inhibit aldosterone synthase. This invention also provides for pharmaceutical compositions comprising the compounds of Formula I or their salts as well as potentially to methods for the treatment, amelioration or prevention of conditions that could be treated by inhibiting aldosterone synthase.

Imidazopyridyl compounds as aldosterone synthase inhibitors

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Glasgow, United Kingdom

Jaiqiang Cai