Slayback Pharma LLC

Jagdish Lotan Lohar

Sumitra Ashokkumar Pillai

Sushant Omprakash Dube

Praveen Kumar Subbappa

Satheesh Balasubramanian

Abhijit Balaji Pawar

Parvateesam Yenda

Girish G Kore

Harish Govindaraja Setty Chinnari

Somashekhar Battini

The present invention relates to liquid pharmaceutical compositions of edaravone. More specifically, stable solutions of edaravone for enteral administration are provided, wherein the composition is stable for extended period of time. The present invention further relates to stable solutions of edaravone, methods for their administration, processes for their production, and use of these compositions for treatment of diseases treatable by edaravone.

Stable pharmaceutical compositions of edaravone

The present invention relates to stable pharmaceutical compositions of dihydroergotamine mesylate or other pharmaceutically acceptable salts thereof and methods for preparing the compositions particularly for the treatment of migraine headaches. The invention further relates to stable injectable composition comprising dihydroergotamine or its pharmaceutically acceptable salts thereof, wherein the composition has a pH from about 5.0 to about 6.0. Further, the present invention relates to a method of treating migraine comprising providing a stable pharmaceutical composition for parenteral administration comprising dihydroergotamine mesylate, wherein the pH of the composition ranges from 5.0 to 6.0 and, wherein the composition comprises no greater than 3% of total impurities as determined by HPLC.

Stable pharmaceutical compositions of dihydroergotamine mesylate

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Pune, India

Jagdish Lotan Lohar