Lysentech Co., Ltd.

Hankuk University of Foreign Studies Research Business Foundation

Jaeyeon Jang

Min Soo Kim

Heejoon Myung

Hye-Won Hong

Jione Pyeon

Young Deuk Kim

Provided are a novel polypeptide having endolysin activity, a fusion protein comprising the polypeptide and an antibiotic active protein, and an antibiotic use against a gram-negative pathogen of the polypeptide and/or fusion protein and/or a use for prevention and/or treatment of gram-negative pathogen infection and/or disease or symptoms related to gram negative pathogen infection.

Polypeptides and antibiotics against gram-negative bacterium comprising the same

Provided are a novel polypeptide, a fusion polypeptide comprising the polypeptide, and a use thereof as an antibiotic. More specifically, provided are a novel polypeptide derived from a bacteriophage, a novel fusion polypeptide comprising cecropin A, and an antibiotic against Gram-negative bacteria comprising the polypeptide and/or the fusion polypeptide.

Polypeptide, fusion polypeptide, and antibiotic against gram-negative bacteria comprising same

Growing community of inventors

Seongnam-si, South Korea

Jaeyeon Jang