Korea Research Institute of Bioscience and Biotechnology

Jae Sung Song

Kyung Seop Ahn

Jae Wha Kim

Sei Ryang Oh

Doo Young Kim

Jung Hee Kim

Hyeong Kyu Lee

Sei-Ryang Oh

Ho Bum Kang

Hyun Woo Oh

Joo Heon Kim

Da Jung Ji

Hyeong-Kyu Lee

InPyo Choi

Ho-Bum Kang

Jang Mi Sun

Jae Jong Go

Piseth Khiev

The present invention relates to an injenane-type diterpene compound derived fromLiou, and a pharmaceutical composition for treating or preventing viral infectious diseases, a health functional food for preventing or ameliorating viral infectious diseases and a composition for enhancing the production of interferon-gamma, which comprise the injenane-type diterpene compound. Furthermore, the present invention relates to a method for preventing or treating viral infectious diseases including administering the composition to a subject having a viral infectious disease occurrence or a risk thereof with a therapeutically effective dose.

Ingenane-type diterpene compound, and pharmaceutical composition for treating or preventing viral infectious diseases containing same

The present invention relates to a pharmaceutical composition for the prevention or treatment of atopy comprising the extract of, the fraction thereof, of the compound isolated from the same as an active ingredient. More precisely, the extract of, the fraction thereof, or the compound isolated from the same, genekwadapnin or yuanhuacine, of the present invention can increase the secretion of cytokine in Th1 immune cells and suppress atopy in the atopy mouse model, so that the extract of, the fraction thereof, or the compound isolated from the same of the present invention can be effectively used for the prevention or treatment of atopy.

Daphne genkwa extracts, and pharmaceutical composition containing fractions of the extracts or compounds separated from the extracts as active ingredients for preventing or treating atopic dermatitis

The present invention relates to an antiviral composition containing anorextract or a fraction thereof as an active ingredient. In detail, extracts oforor fractions thereof can induce the secretion of an immune-related cytokine, interferon-&#x3b3; (IFN-&#x3b3;) in natural killer (NK) cells, and thus exhibit potent antiviral activity and superior effects for viral diseases, and therefore can be effectively used in an antiviral composition.

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Daejeon, South Korea

Jae Sung Song