Samsung Electronics Co., Ltd.

Intellectual Discovery Co., Ltd.

Jae-Min Kang

Kun-soo Shin

Kun-kook Park

Jeong-Dae Suh

Ki-Bong Song

Myung-Ae Chung

Kwan-Su Kim

Cheol-Joo Chae

A method for diagnosing Alzheimer's disease by detecting the presence of beta-amyloid in cells using a phototransistor device. Cells that potentially contain beta-amyloid are provided and labeled with a multi-protein that selectively binds to beta-amyloid if present and that includes streptavidin, biotin and polyethylene glycol connected in sequence with the streptavidin being bound to a magnetic bead and the polyethylene glycol being bound to the beta-amyloid, to provide labeled cells. A phototransistor device including a channel layer is provided and a difference in photocurrent determined corresponding to incident light measured before and after selectively fixing the labeled cells on a surface of the channel layer by applying an external magnetic field effective to attract the magnetic bead to the phototransistor device through a permanent magnet positioned below the channel. Any difference between the first and second photocurrents indicates the presence of, and optionally amount of, labeled beta-amyloid in the cells.

Method for early diagnosis of alzheimer'S disease using phototransistor

An apparatus for eliminating motion artifacts in a bio signal includes a bio signal acquisition unit configured to acquire a bio signal from a patient; a reconstruction signal generator configured to generate a reconstruction signal of the acquired bio signal based on a result of comparing the acquired bio signal with a bio signal pattern of the patient generated using a bio signal measured from the patient before acquiring the bio signal from the patient; and a motion artifact elimination unit configured to eliminate motion artifacts in the acquired bio signal based on a difference between the reconstruction signal and the acquired bio signal.

Method and apparatus for eliminating motion artifacts of bio signal using personalized bio signal pattern

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Seoul, South Korea

Jae-Min Kang