Genechem Inc.

Jae-Kyung Song

Sang Mi Lee

Dae Hee Kim

Byung-Gee Kim

Yun Hee Choi

Won Min Seo

Ji Young Yang

Sun Youp Kang

Jin Suk Woo

The present invention relates to a method for preparing a sialic acid derivative characterized by performing both of a process for preparing CMP-N-acetylneuraminic acid using N-acetyl-D-glucosamine and a process for preparing the sialic acid (neuraminic acid) derivative that combines a sialic acid with a galactose derivative or a lactose derivative, together, in one reactor. According to the method for preparing a sialic acid derivative of the present invention, expensive cytidine 5'-monophosphate (CMP) is capable of being recycled in a reactor, such that an amount of the CMP introduced into the reactor may be reduced, and the sialic acid derivative is capable of being prepared at a significantly high efficiency by using cheap N-acetyl-D-glucosamine, and pyruvate as substrates.

Method for preparing sialic acid derivative

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Chungcheongnam-do, South Korea

Jae-Kyung Song