Yonsei University

Newtree Co., Ltd.

Cosmax Nbt, Inc.

Cosmax Ns, Inc.

Biocare Co., Ltd.

Aat Costech Co., Ltd.

Jae Kwan Hwang

Chang Hee Kim

Mi Bo Kim

Jeong Hwan Kim

Jin Hak Kim

Su Young Choi

Do Un Kim

Heechul Chung

Mi-Bo Kim

Jae Youn Chung

Doun Kim

Ji Hwan Jang

Jeong Ho Geum

Joon Hyung Lee

Hae Ji Lee

Hee Chul Chung

Hyeongmin Kim

Se In Lee

Min Son Kweon

Seon Wook Woo

Seung Tae Su

Yu-Mi Cho

Ji Hee Yoo

Gyu Hoi Kim

Jong Wook Kim

Jun Gon Yun

Do Wan Kwon

Hyun In Oh

The present invention relates to a composition for preventing or treating muscular diseases, or for improving muscular functions, containing gagnlioside. More specifically, the present invention relates to a pharmaceutical composition for preventing or treating muscular diseases, a food composition for preventing or alleviating muscular diseases, or a cosmetic composition for preventing or alleviating muscular diseases, all of which comprise gagnlioside, which can increase the expression of proteins associated with muscle protein synthesis and muscle mass growth in muscle cells and inhibit the expression of enzymes involved in muscle protein degradation at the mRNA level.

Composition for preventing or treating muscular diseases, or for improving muscular functions, containing ganglioside

The present invention relates to a composition for preventing or treating a muscle disorder, which includes a chrysanthemum extract or 3,5-dicaffeoylquinic acid as an active ingredient, and specifically, it may be used to reduce mRNA expression of atrogin-1 and MuRF1, which are main biomarkers involved in muscle protein degradation and increase mRNA expression of the mTOR protein, which is a main biomarker involved in muscle protein formation, and myogenin and MyoD, which are biomarkers related to muscle differentiation, thereby reducing muscle loss, and thus the chrysanthemum extract or 3,5-dicaffeoylquinic acid can be used in prevention and treatment of a muscle disorder, or improvement in muscle function. In addition, the chrysanthemum extract or 3,5-dicaffeoylquinic acid increases the activity of SIRT1 and PGC-1&#x3b1;, which are the main biomarkers involved in exercise performance, thereby excellently enhancing exercise performance. In addition, the present invention is a natural substance and may be safely used without a side effect, and therefore may be used as a medication, food or a cosmetic.

Composition for improvement of muscle function containing 3,5-dicaffeoylquinic acid or chrysanthemum extract

var.according to the present invention is capable of increasing muscle mass and enhancing muscular function or exercise performance through an effect of promoting mRNA or protein expression and the activity of a gene involved in muscle functions, muscle mass increase of differentiation of muscle cells; can prevent, treat or ameliorate a decline in exercise performance, a decline in muscle function, muscle loss, etc. caused by various diseases; and may be effectively used for medicines or food products, etc., since it has no side effects in the body as natural substance.

Composition for improving muscular function or for enhancing exercise performance comprising vigna angularis var. angularis

A composition for preventing or treating muscle diseases or improving muscular function, containing fucosterol,, adried powder, aextract,, adried powder or aextract is disclosed. Fucosterol,, adried powder, aextract,, adried powder or aextract increases the protein expression of p-mTOR, which is a main gene involved in muscle protein synthesis, inhibits the mRNA expression of MuRF-1 and atrogin-1 involved in muscle protein degradation, and increases the mRNA expression of MyoD and myogenin involved in muscle differentiation, thereby having an effect of remarkably increasing muscular function. In addition, the composition can be safely used without side effects, thereby being usable in medicine, food, cosmetic products, livestock feed, a feed additive and the like.

Composition for preventing, alleviating or treating muscle diseases or improving muscular function

The present invention relates to a novel use of fucosterol and, more specifically, to a composition for skin whitening or composition for skin moisturizing, which is characterized by containing fucosterol. Fucosterol of chemical formula 1 below has an excellent whitening effect of inhibiting melanin generation and tyrosinase activity, and thus can be used as an active ingredient of a cosmetic composition for whitening, a food composition, or a pharmaceutical composition. Furthermore, the fucosterol of chemical formula 1 below has an excellent moisturizing function by forming dead skin cell membranes, promoting the differentiation of dead skin cells, and generating natural moisturization factors, and thus can be used as an active ingredient of a cosmetic composition for moisturizing, a food composition, or a pharmaceutical composition 

Composition containing fucosterol for skin whitening or moisturizing

The present invention relates to a new use of lignan-type compounds or an extract of nutmeg or aril of nutmeg comprising the same. More particularly, the present invention relates to a composition for skin whitening comprising a lignan-type compound or an extract of nutmeg or aril of nutmeg comprising the same. Because the lignan compound represented by Chemical Formulas 1 to 3 or the extract of nutmeg or aril of nutmeg has superior skin whitening activity by inhibiting melanin production and tyrosinase activity, it can be used for the preparation of a cosmetic composition, food composition or pharmaceutical composition for skin whitening.

Use of lignan-type compounds or extract of nutmeg or aril of nutmeg comprising the same

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Seoul, South Korea

Jae Kwan Hwang