Hologic, Inc.

Siemens Medical Solutions Usa, Inc.

The Cleveland Clinic Foundation

Singapore General Hospital

Arjae Spectral Enterprises

Jae Koul Kim

Cameron Anthony Piron

Arsen R Hajian

Richard D White

Randolph M Setser

Kevin K'o Wen Chen

Arthur E Stillman

Ralf B Loeffler

An improved method for reconstruction of medical images includes the acquisition of k-space data through MRI imaging. Subsequently, subsets of the k-space data are transformed into intermediate images by performing an inverse Fourier transform on selected sets. These intermediate images are saved to a PACS or other memory storage, and can be recalled later to reconstruct an image. By selecting various intermediate images, a user can vary both the spatial and temporal resolution of the reconstructed image after acquisition, thereby providing adaptive reconstruction of images without the need to acquire new data.

Post-acquisition adaptive reconstruction of MRI data

This document describes a general system for noise reduction, as well as a specific system for Magnetic Resonance Imaging (MRI) and Nuclear Quadrupole Resonance (NQR). The general system, which is called Calculated Readout by Spectral Parallelism (CRISP), involves reconstruction and recombination of frequency-limited broadband data using separate narrowband data channels to create images or signal profiles. A multi-channel CRISP system can perform this separation using (1) frequency tuned hardware, (2) a frequency filter-bank (or equivalent), or (3) a combination of implementations (1) and (2). This system significantly reduces what we call cross-frequency noise, thereby increasing signal-to-noise-ratio (SNR). A multi-channel CRISP system applicable to MRI and NQR are described.

Noise reduction apparatus, systems, and methods

A method of magnetic resonance imaging of anatomy that is subject to a movement cycle (e.g., the heart during a cardiac cycle), comprising: administering a magnetic resonance contrast agent; waiting a period of time until the contrast agent is effective to cause selected portions of the anatomy (e.g., macrotic cardiac tissue) to have a different Trecovery rate from that of other portions (normal cardiac tissue); administering a plurality of inversion recovery pulses spaced in time; acquiring image data at a data acquisition time that is spaced in time by a known time interval following an inversion recovery pulse; varying the time within the movement cycle at which the inversion recovery pulses are administered so that the associated data acquisition times are at a plurality of phases of the movement cycle; processing image data acquired at a phase of the movement cycle to produce at least a portion of an image frame at that phase; and performing the processing for a plurality of phases of the movement cycle to produce a plurality of image frames corresponding to a plurality of phases

Acquiring contrast-enhanced, T1 weighted, cine magnetic resonance images

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Tucson, AZ, United States of America

Jae Koul Kim