Cellsafe Co., Ltd.

B & C Biopharm

Jae-Jin Han

Sang-jin Park

Jong-Woo Kim

Geun-Hyung Lee

Sang-Wook Lee

Eul-Yong Park

Joong-Chul Shin

Provided is a bone-transplant or bone-filling composition, which comprises a dihydroxybenzoic acid derivative which has been newly demonstrated to increase the activity of osteoblasts and so induce bone formation.

Bone-transplant or bone-filling composition comprising a dihydroxybenzoic acid derivative

Provided is a method for culturing cells, which prevents the possibility ofcontamination by culturing the cells using biomass extract obtained by culturing a strain with amphidinol productivity, preferably a strain such as, and the like belonging to Dinoflagellates, or using a fraction obtained from the extract; and a method for removingcontamination of the cells by culturing the cells contaminated byusing the amphidinol derivatives. In addition, provided is a method for removingcontamination of the cells, including a combination of single cell-isolating enzyme solution treatment and cell aggregate removal.

Method for culturing mycoplasma contamination-free cells and method for removing mycoplasma contamination of cells

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The present invention relates to 6-(4-substituted-anilino)pyrimidine derivatives useful as an antiviral agent, and more particularly novel 6-(4-substituted-anilino)pyrimidine derivatives having an excellent inhibitory effect on replication of Hepatitis C virus; HCV), represented by the following formula I: in which R represents a C-Cstraight or branched alkoxycarbonyl group, heterocycliccarbonyl group or carboxyalkyl group; and pharmaceutically acceptable salts thereof, a preparation method thereof, and an antiviral pharmaceutical composition comprising the compound as an effective ingredient. The 6-(4-substituted-anilino)pyrimidine derivatives according to the present invention have an excellent inhibitory effect on replication of Hepatitis C virus (HCV) and thus can be advantageously used as a therapeutic or prophylactic agent of hepatitis C.

6-(4-substituted-anilino)pyrimidine derivatives, method for preparation thereof and antiviral pharmaceutical composition comprising the same

The present invention relates to 6-methylpyridine derivatives useful as an antiviral agent. More particularly, the present invention relates to novel 6-methylpyridine derivatives having an excellent inhibitory effect on replication of Hepatitis C virus (HCV), or pharmaceutically acceptable salts thereof, to a method for preparing thereof, and to an antiviral pharmaceutical composition comprising the compound as an active ingredient. The 6-methylpyridine derivatives of the present invention have an excellent inhibitory effect on replication of hepatitis C virus and thus can be advantageously used as a therapeutic or prophylactic agent of hepatitis C 

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Yongin-si, South Korea

Jae-Jin Han