Samsung Electronics Co., Ltd.

Jae Il Lee

Jung Min Kim

Jung-Hoon Lee

JungMin Lee

Dongkyu Shin

Hye Yoon Kang

Eunji Kang

Soshin Ahn

Jieun Han

Jung-Min Lee

Jung Min Lee

Jung Wook Lee

Sunghyun Kim

Su Young Chae

Sang Ok Song

Kyoung Hu Lee

Hye Young Suh

Su-Jeong Hwang

Provided is a chemically modified targeting protein, a pharmaceutical composition including the chemically modified targeting protein, a conjugate including the chemically modified targeting protein and a drug, and methods for preparing the same.

Chemically modified targeting protein and use thereof

A three-helix bundle protein, a polynucleotide encoding the three-helix bundle protein, a method of preparing the three-helix bundle protein, and a method of treating a cancer using the three-helix bundle protein.

Three-helix bundle protein and use thereof

A protein complex comprising a first polypeptide comprising a first antigen-binding region; a second polypeptide comprising a second antigen-binding region; and a linker connecting the first polypeptide and the second polypeptide, wherein the first antigen-binding region is a single stranded polypeptide comprising a first light chain antigen-binding region and a first heavy chain antigen-binding region, the second antigen-binding region is a single stranded polypeptide comprising a second light chain antigen-binding region and a second heavy chain antigen-binding region, and the linker connects the C-terminal of the first polypeptide and the N-terminal of the second polypeptide, and comprises a tag including a cleavable amino acid sequence at one terminal or both terminals of the linker; as well as a bispecific antibody derived from the protein complex, and related compositions and methods.

Protein complex, bispecific antibody including the protein complex, and method of preparation thereof

In one example embodiment of the inventive concepts, an adaptive data backup method performed in a memory system including a non-volatile multi-level cell memory device includes receiving a write command from a host and determining a backup data size which is a size of data to be backed up among data requested to be written in the write command. The adaptive data backup method further includes selecting a backup type among at least two different backup types, based on the backup data size and backing up the data according to the selected backup type.

Non-volatile multi-level cell memory system and method of performing adaptive data back-up in the system

A fusion protein including granzyme B, a cell penetrating peptide, a cleavage site, and a targeting moiety, a composition for cell membrane penetration comprising the fusion protein, and an anticancer composition comprising the fusion protein.

Fusion protein comprising granzyme B and use thereof

A fusion protein including a targeting moiety, a cleavage site, and a cell membrane penetrating domain, a conjugate including the fusion protein and a bioactive molecule, and methods employing the fusion protein and the conjugate are provided.

Fusion protein comprising targeting moiety, cleavage site, and cell membrane penetrating domain, and use thereof

A p16 protein variant; a polynucleotide encoding the p16 protein variant; a method for preparing the p16 protein variant; a pharmaceutical composition comprising the p16 protein variant; a method for preventing and/or treating cancer comprising administering the p16 protein variant to a subject; and use of the p16 protein variant in the prophylaxis and/or therapy of cancer.

p16 protein variant and use thereof for preventing or treating cancer

A polypeptide binding to Annexin A1, an antagonist against Annexin A1 including the polypeptide, an anti-Annexin A1 antibody including the polypeptide or an antigen-binding fragment thereof, and methods of preventing, treating and/or diagnosing a disease, including administering the antagonist and/or the antibody or an antigen-binding fragment thereof to a subject.

Polypeptide binding to annexin A1 and use thereof

A p15 protein variant; a polynucleotide encoding the p15 protein variant; a method for preparing the p15 protein variant; a pharmaceutical composition comprising the p15 protein variant; and a method for preventing and/or treating cancer comprising administering the p15 protein variant to a subject.

P15 protein variant and use thereof for preventing or treating cancer

A cell having a surface coated with Annexin A1 (ANXA1), a method of detecting a substance binding to ANXA1 using the cell, and a method of preparing the cell are provided.

Cell with surface coated with ANXA1 and use thereof

A leucine zipper variant, a polynucleotide encoding the leucine zipper variant, a method of preparing a leucine zipper variant, a method of inhibiting HDM2- and/or HDMX using the leucine zipper variant, and a method of the prevention and/or treatment of cancer using the leucine zipper variant.

Growing community of inventors

Yongin-si, South Korea

Jae Il Lee