Celltrion Inc.

Optipharm Co., Ltd

Jae Bin Lee

So Young Kim

Dong Yun Lee

Su Jung Kim

Jun Seok Oh

Joon Won Lee

Yeon Kyeong Shin

Won Yong Han

Kwang Woo Kim

Hye Young Kang

Ji Won Roh

Ji Min Kwak

Jae Kyung Park

Ki Myung Choi

Joo Hyun Shim

The present disclosure provides a surface-modified alginate micro-capsule having a core-shell structure in which a core is fluidizable phase alginate, and a shell is alginate hydrogel crosslinked with epigallocatechin gallate dimer, a preparation method thereof, and a cell encapsulation method using the same.

Alginate microcapsules for cell encapsulation and, manufacturing method therefor

A stable liquid pharmaceutical formulation according to the present invention includes an antibody or antigen-binding fragment thereof, a surfactant, a sugar or a sugar derivative, a buffer, and a stabilizer. The stable liquid pharmaceutical formulation according to the present invention has low viscosity not only when antibody content is low but also when antibody content is high, and exhibits superior long-term storage stability based on superior stability observed under accelerated conditions and harsh conditions.

Stable liquid pharmaceutical preparation

Growing community of inventors

Incheon, South Korea

Jae Bin Lee