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Centre National De La Recherche Scientifique

Université Joseph Fourier

Institute of Biochemistry and Biophysics—polish Academy of Sciences

Jadwiga Chroboczek

Pascal Fender

Wlodzimierz Zagorski

Renata Grzela

Use of VPg proteins, fragments or analogs thereof having the ability to bind an eukaryotic initiation factor eIF4E, for inhibiting cell-proliferation.

Cell-proliferation inhibiting VPg proteins, fragments or analogs thereof and their applications

The invention concerns transfecting peptide vector, a composition containing said vector and their applications for treating and preventing diseases in human beings and animals. Said vector for transfecting a chemical substance selected in the group consisting of nucleic acid sequences, proteins, peptides and pharmacologically active substances, contains besides said chemical substance, at least a transfecting peptide derived entirely or partially from an adenovirus fibre and comprising at least a zone consisting of at least 50% hydrophobic amino acids selected in the group consisting of alanine, valine, phenylamine, isoleucine, leucine, proline and methionine.

Transfecting peptide vector, composition containing same and applications

Dodecahedral adenoviral protein complex, composition containing same and

Growing community of inventors

Grenoble, France

Jadwiga Chroboczek