Ares Trading S.a.

Biogen Idec Ma Inc.

The Feinstein Institute for Medical Research

Jadwiga Bienkowska

Christine Power

Richard Fagan

Stephen Fitzgerald

Melanie Yorke

John P Carulli

Melanie Yorke-Smith

Peter K Gregersen

Franak Batliwalla

Chunyu Liu

This invention relates to a novel protein, termed INSP201, herein identified as a cell surface glycoprotein, and to the use of this protein and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease.

Cell surface glycoprotein

This invention relates to the novel protein, termed INSP163, herein identified as a secreted protein containing a jelly-roll fold, in particular, as a member of the TNF (tumor necrosis factor)-like family of cytokines, specifically as a C1q-like protein and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.

Isolated INSP 163 protein

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Cambridge, MA, United States of America

Jadwiga Bienkowska