Merck Patent Gesellschaft MIT Beschrankter Haftung

Jacques De Peyer

Rolf Gericke

Manfred Baumgarth

Rolf Bergmann

Ingeborg Lues

Hanns Wurziger

Inge Lues

Gunther Hausler

Chroman derivatives of the formula I ##STR1## wherein R.sup.1 to R.sup.8 have the meanings defined herein, and their salts have an effect on the cardiovascular system.

Chroman derivatives

Novel chroman derivatives of the formula I ##STR1## in which X is O or NR.sup.11,

Novel chroman derivatives of the formula I ##STR1## in which R.sup.1 to R.sup.6 and Z have the meanings given in Patent Claim 1, and their salts show effects on the cardiovascular system and can be used for the treatment or prophylaxis of cardiac insufficiency, angina pectoris, high blood pressure, incontinence and alopecia.

Oxodihydropyridyl chroman derivatives

New tetralin derivatives of the formula I ##STR1## wherein R.sup.1 to R.sup.8 and Z have the meanings indicated herein and salts thereof, exhibit an effect on the cardiovascular system.

Tetralin compounds

Novel chroman derivatives of the formula I ##STR1## in which R.sup.1 to R.sup.10 have the meanings given in patent claim 1, and their salts show effects on the cardiovascular system and can be used for the treatment or prophylaxis of cardiac insufficiency, angina pectoris, high blood pressure, incontinence and alopecia.

Novel benzoxazine derivatives of the formula I ##STR1## wherein R.sup.1 to R.sup.5 have the meanings defined herein, and salts thereof, exhibit effects on the cardiovascular system.

4-(pyridyl)- and 4-(oxo-pyridyl)-1,3-benzoxazines

A compound of the formula: ##STR1## where in x-y is --CO--CH.sub.2 --, --COCR.sup.10-, --CHOHCHR.sup.8-, --CH.dbd.CR.sup.8 -- or ##STR2## and R.sup.9 is various, R.sup.1 and R.sup.8 are alkyl, R.sub.2 is H or alkyl and R.sup.1 and R.sup.2 are alkylene, are disclosed as useful as intermediates for cardiovascular agents.

An azachroman derivative of the formula ##STR1## wherein Z is

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Jacques De Peyer