Biomerieux, Inc.

Biomerieux Sa

Other

Jacques Dachaud

Bruno Colin

Bryan W Kluttz

Luigi Catanzariti

Michel Guy

Geoff A McKinley

Louis Graziano

Fabio Gennari

Christopher Cotter

Cecile Jaravel

Cécile Paris

Jean-Claude Raymond

David Mosticone

Frédéric Foucault

Marie Privat

Pierre Imbaud

Edgar Minassian

Fabienne Made

Fabien Dachaud

Corinne De La Foata

A device and method preparing a sample that may contain a target microorganism, includes: placing the sample in a container including: a device for the capture and/or concentration of a target microorganism or of a protein therefrom, including a capture and/or concentration support; a receptacle including; inlet and fluid guides, a device controlling the sample volume transferred from the fluid guide to the capture and/or concentration device through the inlet orifice, an outlet orifice; the capture/concentration device being attached to a wall of the receptacle; generating a displacement of all or part of the sample to the fluid guide and a defined sample volume from the fluid guide to the capture and/or concentration device, capturing and/or concentrating, on the capture and/or concentration support, the target microorganism or a protein from the microorganism, the volume of sample crossing the capture and/or concentration support then exiting again through the outlet orifice.

Method and device for preparing samples

A device () for detecting the presence of at least one microorganism in the contents () of a container () comprising a wall with a translucent zone, said detection device () comprising:

Detection device, system and method making it possible to detect the presence of a micro-organism in a sample or inside a container

A device for implementing a test card inside which sequential reactions and fluid transfer operations are performed under the effect of a control integrated into the card; the card includes at least two sequential reaction systems arranged in parallel, each reaction system having at least two fluid transfer systems arranged in series. A test card and the method for implementing the device and the card are also disclosed. The device contains at least one actuator per reaction line, and all the actuators are at a regular distance from one another, with the actuators preferably being equidistant. The invention is particularly applicable for the micromanipulation of fluids in biological applications.

Device for implementing an analysis pack, analysis pack and method using same

An instrument for conducting nucleic acid amplification reactions in a disposable test device. The test device includes a first reaction chamber containing a first nucleic acid amplification reagent (e.g., primers and nucleotides) and a second reaction chamber either containing, or in fluid communication, with a second nucleic acid amplification reagent (e.g., an amplification enzyme such as RT). The instrument includes a support structure receiving the test device. A temperature control system maintains the first reaction chamber at a first elevated temperature but simultaneously maintains the second nucleic acid amplification reagent at a second temperature lower than the first temperature so as to preserve the second nucleic acid amplification reagent. An actuator operates on a fluid conduit in the test device to place the first and second reaction chambers in fluid communication with each other after a reaction has occurred in the first reaction chamber at the first temperature. A pneumatic system is also provided that assists in fluid transfer of a reaction solution from the first chamber to the second chamber.

Nucleic acid amplification reaction station for disposable test devices

The invention concerns a device for performing a reaction or at least two reactions in parallel or in series, and for transferring a fluid flow, consisting of. an upper surface () and a lower surface () mutually linked by an edge (); at least a duct () wherein a fluid flow (F) can be generated by means transferring at least one sample () to be treated and/or analysed, and at least a valve () incorporated in each duct () for directing each sample () thereby controlling the transfers, reactions and analyses in the device. Each valve () consists of two means (and) integral with the device, the first means () being mobile between an inoperative position wherein the fluid transfer () is possible and an active position wherein said transfer cannot take place, and the second means () being mobile between a position wherein it is not in contact with said first means () and an active position wherein it deforms the first means () and it is activated by an actuator external to the device.

Microfluid system for reactions and transfers

A valve (), crossed by at least one channel (), allowing to direct at least one fluid (F) displaced by a transfer device within a test sample card (), the card () featuring two faces (and) connected to one another () () by an edge (). A card equipped with a device allowing several cards equipped with such valves to be implemented is made up of a flexible film (), and/or which can be distorted, part of which is fixed to at least one of the faces (and/or) of said card () on the one hand, and a film compression device (), which can be deactivated on the other hand. In addition, securing is carried out on at least one of the plane faces (and/or), for example, by a securing device located at the level of a recession () peripheral to the valve (), such as a groove (). The valve is particularly applicable in the field of diagnosis.

Valves enabling a liquid to be directed in a diagnostic chart diagnostic charts and diagnostic device comprising several charts

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Besancon, France

Jacques Dachaud