Institut Pasteur

Université Pierre Et Marie Curie (Paris Vi)

Universite De Reims Champagne-ardennes

Jacques Cohen

Luc Montagnier

Pierre Charneau

David Klatzmann

Denise Guetard

Andrew Borman

Caroline Quillent

Jacqueline Donjon De Saint-Martin

Fran&ccedil;ois Clavel

François Clavel

An HIV-1 type (or subtype) O retrovirus protein, or a natural or synthetic polypeptide or peptide including at least a part of said protein, which is capable of being recognized by antibodies isolated from a serum resulting from infection by an HIV-1 type O VAU strain or an HIV-1 type (or subtype) O DUR strain.

Nucleotide sequences of HIV-1 group (or subgroup) O retroviral antigens

A recombinant heteromultimeric protein including at least (a) a polypeptide fusion molecule A consisting of a C4BP &#x3b1;-chain C-terminal fragment and a polypeptide fragment heterologous to said &#x3b1; chain, and (b) a polypeptide fusion molecule B consisting of a C4BP &#x3b2;-chain C-terminal fragment and a polypeptide fragment heterologous to said &#x3b2;-chain, wherein (a) and (b) are linked in the C-terminal portion to form said multimeric protein.

&#x3b1;-&#x3b2; C4BP-type recombinant heteromultimeric proteins

A recombinant heteromultimeric protein including at least (a) a polypeptide fusion molecule A consisting of a C4BP &#x3b1;-chain C-terminal fragment and a polypeptide fragment heterologous to said &#x3b1;-chain, and (a) a polypeptide fusion molecule B consisting of a C4BP &#x3b2;-chain C-terminal fragment and a polypeptide fragment heterologous to said &#x3b2;-chain, wherein (a) and (b) are linked in the C-terminal portion to form said multimeric protein.

An HIV-1 type (or subtype) O retrovirus protein, or a natural or synthetic polypeptide or peptide including at least a part of said protein, which is capable of being recognised by antibodies isolated from a serum resulting from infection by an HIV-1 type O VAU strain or an HIV-1 type (or subtype) O DUR strain.

Nucleotide sequences of HIV-1 type (or subtype) O retrovirus antigens

Growing community of inventors

Reims, France

Jacques Cohen