Albert Einstein College of Medicine

Caprion Proteomics Inc.

Jacqueline Michele Achkar

Jonathan R Lai

Tingting Chen

Elise Ishida

Daniel Hofmann

Arturo Casadevall

Eustache Paramithiotis

Pascal Croteau

Rafael Prados-Rosales

Anke Ziegenbalg

Provided are high affinitycapsule-specific antibodies and fragments thereof, as well as methods of use and devices employing such antibodies and/or fragments.

High-affinitycapsule-specific human monoclonal antibody

The present invention provides biomarkers, methods and kits for diagnosing active tuberculosis in a subject, methods and kits for monitoring the effectiveness of treatment for active TB, as well as methods for identifying a compound that can treat TB reduce or inhibit the development of complications associated with the disease in a subject, and methods to treat active TB.

Tuberculosis biomarkers and uses thereof

The present invention relates to methods and kits for detecting active tuberculosis infection in a subject using serological techniques and a first agent capable of binding an IgG, IgA and/or IgM directed to the first protein present in or on amembrane vesicle or aCalmette-Guerin (BCG) membrane vesicle. Also provided are methods of treating a subject with an active tuberculosis disease.

Serologic test for the rapid diagnosis of active tuberculosis

Growing community of inventors

Brooklyn, NY, United States of America

Jacqueline Michele Achkar