Other

Cyberonics, Inc.

Jacob Zabara

Reese S Terry, Jr

Joachim F Wernicke

Burke T Barrett

Steven M Parnis

An electromagnetic radiation treatment regime includes identifying a target area of a patient. In one embodiment, the target area is the vagus nerve. An electromagnetic radiation source, for example, a low frequency and/or radio frequency electromagnetic radiation source, is selected, along with treatment session parameters, such as, pulse frequency, pulse duration, electrical current, magnetic flux density, and/or treatment session exposure time. An amount of electromagnetic radiation is applied to the target area, and a response to the electromagnetic radiation in the target area is measured. Based on an evaluation of the measured response, the treatment parameters may be modified for one or more subsequent electromagnetic radiation treatment session.

Electromagnetic radiation treatment

An electromagnetic radiation treatment regime includes identifying a target area of a patient. An electromagnetic radiation source, for example, a low frequency and/or radio frequency electromagnetic radiation source, is selected, along with treatment session parameters, such as, pulse frequency, pulse duration, electrical current, magnetic flux density, and/or treatment session exposure time. An amount of electromagnetic radiation is applied to the target area, and a response to the electromagnetic radiation in the target area is measured. Based on an evaluation of the measured response, the treatment parameters may be modified for one or more subsequent electromagnetic radiation treatment session.

A method of treating a patient with at least one substance addiction, which comprises directly stimulating a cranial nerve, such as the vagus nerve, of a patient with an electrical pulse signal defined by a plurality of parameters to provide a therapy regimen for alleviating a symptom associated with the substance addiction.

Cranial nerve stimulation for treatment of substance addiction

An electromagnetic radiation treatment regime includes identifying a target area of a patient that comprises at least some cancer cells, or other cells amenable to pathological genetic regulations. An electromagnetic radiation source, for example, a low frequency and/or radio frequency electromagnetic radiation source, is selected, along with treatment session parameters, such as, pulse frequency, pulse duration, electrical current, magnetic flux density, and/or treatment session exposure time. An amount of electromagnetic radiation is applied to the target area, and a response to the electromagnetic radiation by at least some of the cancer cells in the target area is measured. Based on an evaluation of the measured response, the treatment parameters may be modified for one or more subsequent electromagnetic radiation treatment session.

Electromagnetic radiation treatment for cancer and pathological genetic regulations

Systems and methods for treating neuro-psychiatric disorders, such as depression or schizophrenia, and/or other illnesses are disclosed. A patient is diagnosed with a particular neuro-psychiatric disorder or other illness. An electric nerve stimulation (ENS) technique, such as vagus nerve stimulation (VNS), is administered to the patient in conjunction with a magnetic nerve stimulation (MNS) technique. The magnetic nerve stimulation (MNS) technique includes applying a magnetic field to a pre-selected synaptic region of a brain of the patient based on the diagnosis. A physiological response of the brain, such as electroencephalogram (EEG) activity, is monitored. One or more parameters of the magnetic field may be selectively adapted in response to the monitored physiological response. The administration of the ENS technique and the MNS technique may be performed simultaneously, in serial order, or in alternating order depending on the diagnosis.

Systems and methods for therapeutically treating neuro-psychiatric disorders and other illnesses

A method and apparatus are disclosed for treating patients suffering from severe, unrelenting pain. A therapeutic stimulation signal is selectively applied from a stimulus generator, when activated, to at least some of plural electrodes implanted in stimulating relation to at least two nerves among the patient's trigeminal, vagus, glossopharyngeal and sympathetic nerves, and the stimulus generator is activated to generate the therapeutic stimulation signal to alleviate the pain under treatment. Alternatively, the therapeutic stimulation signal is selectively applied to at least one electrode implanted in stimulating relation to at least one of the patient's trigeminal, vagus, glossopharyngeal and sympathetic nerves, and if the selected nerve is the vagus nerve, the signal is applied to a supra-diaphragmatic or sub-diaphragmatic site, either unilaterally or bilaterally to one or both branches, respectively, of the vagus nerve.

Nerve stimulation as a treatment for pain

Heart rhythm is stabilized within the heart's free running cycle by detecting arrhythmias in a mammalian subject, and then electronically stimulating the subject's vagus and cardiac sympathetic nerves. More specifically, vagus efferents are stimulated to directly cause heart rate to slow down, while cardiac sympathetic nerve efferents are stimulated to cause the heart rate to quicken. Simultaneously, afferents from vagus and/or cardiac sympathetic nerves induce the brain to employ the brain's natural mechanisms of heart rhythm control. Such nerve stimulation works in harmony with the body's natural mechanisms of heart rhythm control.

Heart rhythm stabilization using a neurocybernetic prosthesis

The treatment, control or prevention of medical, psychiatric or neurological disorders may be accomplished by application of modulating electric signals to one or both of a patient's trigeminal and glossopharyngeal nerves. The disorders treatable, controllable or preventable by such nerve stimulation include voluntary and involuntary disorders, migraine, epileptic seizure, motor disorders, Parkinson's disease, cerebral palsy, spasticity, chronic nervous illnesses and involuntary movement; pancreatic endocrine disorders including diabetes and hypoglycemia; dementia including cortical, subcortical, multi-infarct, Alzheimer's disease and Pick's disease; sleep disorders including central sleep apnea, insomnia and hypersomnia; eating disorders including anorexia nervosa, bulimia and compulsive overeating; and neuropsychiatric disorders including schizophrenia, depression and borderline personality disorder.

Cranial nerve stimulation treatments using neurocybernetic prosthesis

Method and apparatus for treating and controlling neuropsychiatric disorders including schizophrenia, depression, and borderline personality disorder by selectively applying a predetermined electrical signal to the patient's vagus nerve for stimulation thereof to alleviate the symptoms of the disorder being treated. The electrical signal may be applied continuously, periodically, or intermittently to the vagus nerve depending, in part, on the nature of the disorder being treated. In certain instances, the electrical signal is applied upon detection of an event indicative of onset of the disorder. In other instances, the electrical signal is selectively applied at will to the vagus nerve, such as by patient activation of the signal generator. Parameter values of the electrical signal including pulse width, output current, frequency, on time and off time, are selectively programmable.

Treatment of neuropsychiatric disorders by nerve stimulation

A neurocybernetic prosthesis for controlling or preventing epileptic seizures and other motor disorders includes a pulse generator which generates electrical pulses having a frequency of between 30 and 300 cycles per second, a pulse duration of between 0.3 and 1 millisecond and a constant current of between 1 and 20 milliamperes. The generator is enclosed in an epoxy-titanium shell and is implanted in the body, preferably in the axilla. Electrode leads pass from the generator through a subcutaneous tunnel and terminate in an electrode patch on the vagus nerve. Provisions are made for varying the electrical signal from the generator after it has been implanted to 'tune' the same to the patient. The prosthesis may be designed to be turned on manually when the patient senses the imminence of a convulsion. Alternatively, sensors may be provided for determining changes in the values of state parameters such as electroencephalographic waves which precede a convulsion. The pulse generator can then be turned on automatically in response to the sensors.

Neurocybernetic prosthesis

A neurocybernetic prosthesis for controlling or preventing epileptic seizures and other motor disorders includes a pulse generator which generates electrical pulses having a frequency of between 30 and 300 cycles per second, a pulse duration of between 0.3 and 1 millisecond and a constant current of between 1 and 20 milliamperes. The generator is enclosed in an epoxy-titanium shell and is implanted in the body, preferably in the axilla. Electrode leads pass from the generator through a subcutaneous tunnel and terminate in an electrode patch on the vagus nerve. Provisions are made for varying the electrical signal from the generator after it has been implanted to 'tune' the same to the patient. The prosthesis may be designed to be turned on manually when the patient senses the imminence of a convulsion. Alternatively, sensors may be provided for determining changes in the values of state parameters such as electrocencephalographic waves which precede a convulsion. The pulse generator can then be turned on automatically in response to the sensors.

Growing community of inventors

Miami Beach, FL, United States of America

Jacob Zabara