Itamar Medical Ltd.

Itamar Medical (c.m.) 1997 Ltd.

Jacob Sheffy

Robert P Schnall

Peretz Lavie

Daniel A Goor

Sarah Herscovici-Cohen

Giora Pillar

Apparatus for monitoring arterial pulse waves includes at least one separator ring receivable on at least one digit of a limb effective to tether a feed tube supplying a measuring device to a digit. Each separator ring is of a compliant material, of a non-interrupted tubular configuration, designed to avoid interference of blood supply to or from the digit to which it is applied, and of sufficient resilience and thickness to enable it to distance each adjacent digit from a digit mounted tubular socket probe so as to prevent contact between the tubular socket probe and adjacent digits, without interference to blood circulation, irrespective of the thickness of the digit on which the separator ring is received.

Apparatus for monitoring arterial pulse waves in diagnosing various medical conditions

A method and apparatus for detecting and distinguishing epochs of deep-sleep from epochs of light-sleep of a subject by sensing by a peripheral pulse signal related to the systemic circulation of the subject, preferably a peripheral arterial tone (PAT) sensor for sensing pulsatile arterial volume changes in a digit (e.g., a finger) of the subject reflecting sympathetic tone variations; analyzing the sensed pulse signals for determining therefrom a number of features, particularly seven specific variables in each of two time periods; and utilizing the results of the analysis for determining whether the epoch detected is a light-sleep epoch or a deep-sleep epoch.

Non invasive method and apparatus for determining light-sleep and deep-sleep stages

Method and apparatus for monitoring the sleep state condition of an individual by using an external probe applied to a peripheral body location, such as the individual's finger or toe, for detecting changes in the peripheral vascular bed volume of the individual. A predetermined pressure field is applied to the distal end of the peripheral body location, including its distal-most extremity, to prevent the occurrence of venous pooling within and distal to the peripheral body location. The probe produces an output corresponding to changes in the peripheral arterial bed volume at the peripheral body location, which output provides an indication of the sleep state condition of the individual. Such information is useful in diagnosing and/or in treating, a number of sleep disorders as well as other conditions, such as impotence, diabetes, and various disorders in children.

Method and apparatus for the non-invasive detection of particular sleep-state conditions by monitoring the peripheral vascular system

A method and apparatus for non-invasively evaluating endothelial activity in a patient, particularly for indicating the presence of an endothelial dysfunction condition, by applying an occluding pressure to a predetermined part of an arm or leg of the patient to occlude arterial blood flow therein; maintaining the occluding pressure for a predetermined time period; removing the occluding pressure after the elapse of the predetermined time period to restore arterial blood flow; monitoring a digit of the arm or leg by a digit-probe for changes in the peripheral arterial tone therein before and after the application of the occluding pressure to the arm or leg of the patient; and utilizing any detected changes in the peripheral arterial tone for evaluating endothelial activity in the patient. Particularly important advantages are provided when the occluding cuff is applied to the digit of the patient receiving the monitoring digit-probe, on the proximal side thereof with respect to the patient's heart, and also when a reference digit-probe is applied to another digit, not influenced by the occluding pressure, to compensate for shifts inherent to vascular beds.

Method and apparatus for non-invasively evaluating endothelial activity in a patient

A method and apparatus for non-invasively determining a physiological condition. The method can include steps of monitoring peripheral arterial tone using an external sensor, detecting a change in the peripheral arterial tone, and determining the physiological condition when a specific change in the peripheral arterial tone has been detected. The physiological condition may be a cardiovascular disease state or endothelial dysfunction, for example. The apparatus can include a probe applied to a subject's digit for sensing peripheral arterial tone and outputting a corresponding signal, and a processor which processes the signal and provides an output from which the physiological condition can be determined or which determines the physiological condition based on the signal.

Method and apparatus for the non-invasive detection of medical conditions by monitoring peripheral arterial tone

A method and an apparatus for non-invasive detection of a physiological state or medical condition are disclosed. The method provides an indication of such state or condition such as myocardial ischemia or sleep apnea, by detecting the peripheral arterial tone's response to such state or condition, based on monitoring changes in peripheral arterial tone and determining that a change in the condition of the patient has occurred when a specific change in the peripheral arterial tone has been detected. A static pressure field is applied around the distal part of a digit of the subject. Peripheral arterial tone changes and related volume changes in the distal part of the digit are detected to thereby detect or monitor a physiological state or medical condition. The apparatus includes a finger probe (,), in the form of a tube (,) accommodating the patient's finger, which is designed to apply pressure, and a contiguous pressure cuff (,) which extends the boundary of the pressure field. The finger probe (,) either includes or is associated with a signal sensor/transducer (,).

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Haifa, Israel

Jacob Sheffy