Battelle Memorial Institute

Jacob Lilly

Anthony David Duong

Stephanie Kute

Cherry Gupta

Danielle J Huk

Kenneth R Sims, Jr

Mike Koeris

Ramanathan S Lalgudi

Amy M Heintz

Patrick Ganzer

Krenar Shqau

Katherine M Palmer

Mingming Zhang

The invention relates to polymer nanoparticle and DNA nanostructure delivery compositions for non-viral delivery, and methods therefor. More particularly, the invention relates to polymer nanoparticle delivery compositions, such as reversible addition-fragmentation chain transfer (RAFT) polymer compositions, and DNA nanostructure delivery compositions, such as DNA origami compositions, for the delivery of more than one payload, or for the delivery of a nucleic acid construct payload of 3 kB or more, and methods therefor.

Polymer nanoparticle and DNA nanostructure compositions and methods for non-viral delivery

The invention provides a variety of novel devices, systems, and methods of utilizing mixed-ionic-electronic conductor (MIEC) materials adapted to function with an applied current or potential. The materials, as part of a circuit, are placed in contact with a part of a human or nonhuman animal body. A sodium selective membrane system utilizing the MIEC is also described.

Mixed ionic electronic conductors: devices, systems and methods of use

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Columbus, OH, United States of America

Jacob Lilly