University of California

Librede Inc.

Mt Technologies, Inc.

Jacob J Schmidt

Jason L Poulos

Noah Malmstadt

Tae-joon Jeon

Carlo D Montemagno

Harold G Monbouquette

Steven P Tozzi

Shiva Portonovo

Tae-Joon Jeon

Systems and methods for specific nucleic acid (NA) sequence detection that do not rely on polymerase chain reaction (PCR) for target sequence amplification and do not require any special reagents other than a complementary sequence capture probe conjugated to spherical beads.

Apparatus and method for electrical detection of oligonucleotides through pore blockades

Disclosed herein are compositions, methods, and devices related to bilayer and monolayer membranes, their encapsulation in a hydrogel, and their formation. Methods of using the disclosed compositions and devices are also disclosed.

Formation and encapsulation of molecular bilayer and monolayer membranes

Disclosed herein are devices and methods related to the production and measurements of amphiphilic molecule bilayers, which are useful in high throughput electrophysiological screening and ion channel measurement in bilayers. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Masking apertures enabling automation and solution exchange in sessile bilayers

The invention relates to methods and devices for forming and measuring lipid bilayers, for example, by joining lipid monolayers that self-assemble at the interface of aqueous and organic phases using sessile aqueous droplets in contact with a measurement electrode. At least one of the aqueous solution, the lower aqueous phase, and/or the upper organic phase comprise lipids. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Droplet bilayer formation using throughput liquid handling techniques

Disclosed are biomimetic membrane precursors and membranes formed therefrom. Also disclosed are methods of making biomimetic membrane precursors and membranes formed therefrom. Methods of using, including methods of storing and handling biomimetic membrane precursors and membranes formed therefrom, are also disclosed.

Membrane precursors and membranes formed therefrom

Disclosed herein are compositions, methods, and devices related to bilayer and monolayer membranes, their encapsulation in a hydrogel, and their formation. Methods of using the disclose compositions and devices are also disclosed.

Biological membrane proteins are incorporated into a co-polymer matrix to produce membranes with a wide variety of functionalities. In one form of the invention, a composite membrane incorporates two different proteins which cooperate to produce electricity from light. In another form, water transport proteins are embedded in a membrane to enable water purification.

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Sherman Oaks, CA, United States of America

Jacob J Schmidt