Hdt Bio Corp.

Immune Design Corp.

Jacob Freeman Archer

Steven G Reed

Darrick Carter

Amit Praful Khandhar

Jesse Erasmus

Malcolm Duthie

Bryan J Berube

Lars Peter Aksel Berglund

Peter Lars Aksel Berglund

Tsai-Yu Lin

The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using these compositions as a vaccine for treatment of an infectious disease are also provided.

RNA vaccines against infectious diseases

The disclosure provides compositions, methods of treatment, and methods of making and using compositions to deliver a nucleic acid to a subject. Methods of using the compositions as a COVID-19 vaccine for the treatment of a coronavirus infection are also provided.

SARS-CoV-2 RNA vaccine compositions and methods of use

The present disclosure relates generally to gene delivery using a chimeric, retroviral-RNA replicon vector particle for increased expression of transgenes in a host cell. In particular, the chimeric vectors described herein can be used in any of a variety of settings including gene therapy and vaccine settings.

Retroviral vector for the administration and expression of replicon RNA expressing heterologous nucleic acids

Growing community of inventors

Seattle, WA, United States of America

Jacob Freeman Archer