The University of Queensland

Jacky Yung Suen

David P Fairlie

Robert C Reid

Ligong Liu

Mei Kwan Yau

Lindsay Charles Brown

Abishek Venkatasubramanian Iyer

Mei-Kwan Yau

Junxian Lim

Rink-Jan Lohman

David Paul Fairlie

The present invention provides novel compounds of the Formula (I), pharmaceutical compositions comprising such compounds and methods for using such compounds as tools for biological studies or as agents or drugs for therapies such as metabolic syndrome, obesity, type II diabetes, fibrosis and cardiovascular diseases, whether they are used alone or in combination with other treatment modalities. 

Modulators of protease activated receptors

The present application provides novel compounds of the Formula (I), pharmaceutical compositions comprising such compounds and methods for using such compounds as tools for biological studies or as agents or drugs for modulating Protease Activated Receptor-2 (PAR2) and for treating a subject at risk of&#x2014;or susceptible to&#x2014;a disease or disorder, or having a disease or disorder associated with undesirable PAR2 activity.

The present invention provides novel compounds of the Formula (1), pharmaceutical compositions comprising such compounds and methods for using such compounds as tools for biological studies or as agents or drugs for modulating Protease Activated Receptor-2 (PAR2) and for treating a subject at risk of&#x2014;or susceptible to&#x2014;a disease or disorder, or having a disease or disorder associated with undesirable PAR2 activity. 

Modulations of protease activated receptors

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Brisbane, Australia

Jacky Yung Suen