Dexcom, Inc.

Medtronic Minimed, Inc.

Medtronic Vascular, Inc.

Companion Medical, Inc.

Jack Pryor

Peter C Simpson

Matthew D Wightlin

Apurv Ullas Kamath

Mark C Brister

Sean T Saint

Paul V Goode, Jr

Aarthi Mahalingam

James H Brauker

John Nolting

Vance Swanson

James R Petisce

Steve Masterson

Sebastian Bohm

Arnold Holmquist

Robert James Boock

Paul V Neale

Jacob S Leach

Phong Lieu

Jeff Jackson

James Patrick Thrower

Daiting Rong

Jennifer Blackwell

Michael J Estes

Nelson Quintana

Kum Ming Woo

Jason Mitchell

Melissa A Nicholas

Luis Pestana

Cory Lee McCluskey

Leif N Bowman

Thomas Arnold Peyser

Michael Robert Mensinger

Shawn Larvenz

Jason M Halac

Dubravka Markovic

Mark Dervaes

Antonio C Llevares

Kaushik Aroonkumar Patel

Jasper Benke

Tom Miller

David DeRenzy

Kenneth San Vicente

Eric Johnson

Mohammad Ali Shariati

Lisa Nguyen

Seth R Brunner

Arthur Chee

Monica A Rixman

Alexandra Lynn Carlton

Kristin Koenekamp Cote

Daniel Steven Kline

Disha B Sheth

Antonio Ubach

Naresh Chandra Bhavaraju

Ryan Everett Schoonmaker

Randall Scott Koplin

Justen Deering England

Ellis Garai

Sebastian Böhm

Philip Thomas Pupa

Kathleen Suzanne Hurst

Christopher M Davis

Eli Reihman

Eric Cohen

Hari Hampapuram

Afshin Bazargan

Arturo Garcia

Stephen J Vanslyke

Yuxiang Zhong

Eric Allan Larson

Andrew Attila Pal

Ying Li

Jorge Valdes

John Michael Dobbles

Pratik J Agrawal

Thomas Hall

J Michael Dobbles

Jonathan Hughes

Shanger Wang

Victor Ha

Adam J Livingston

Maria Noel Brown Wells

Todd Andrew Newhouse

Timothy Joseph Goldsmith

Kyle G Neuser

Eric Gobrecht

Leonard Darius Barbod

Mike Mensinger

Ted Tang Lee

Indrawati Gauba

Paul Goode

Stefanie Lynn Mah

Jillian K Allen

Antonio Joao Ubach

Kyle Tinnell Keller

Anna Leigh Rack-Gomer

Curtis Hanson

Lucas Bohnett

Vance E Swanson

A medicine injection pen includes a body, a drive member, a cartridge housing, and a medicine cartridge retained within the cartridge housing. The drive member is configured to move relative to the body and the medicine cartridge defines an interior volume configured to retain a liquid medicine. The drive member is configured to translate a piston within the interior volume toward a dispensing end of the medicine cartridge to dispense at least some of the liquid medicine. The medicine cartridge also includes an insertion port configured to receive a medicine dispensing element therethrough for dispensing a liquid medicine into the interior volume to replace at least some of the liquid medicine dispensed through the dispensing end. Dispensing of the liquid medicine into the interior volume of the medicine cartridge applies a fluid pressure to the piston to translate the piston away from the dispensing end of the medicine cartridge.

Injection pens for medicine administration

Systems and methods of use involving sensors having a signal-to-noise ratio that is substantially unaffected by non-constant noise are provided for continuous analyte measurement in a host. In some embodiments, a continuous analyte measurement system is configured to be wholly, transcutaneously, intravascularly or extracorporeally implanted.

Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise

An accessory for use with a medicine delivery device includes a body configured to attach to a medicine delivery device and a user interface disposed on the body and configured to communicate information to a user. In aspects, the user interface includes first and second lights configured to be selectively illuminated and a first symbol associated with the first light. The first light and the first symbol together indicate an action to be performed when the first light is illuminated. In aspects, the user interface includes red, yellow, and green lights configured to be illuminated in sequential time periods after a dose using the medicine delivery device.

Accessory devices, systems, and methods for medicine administration and tracking

Methods, systems, and devices are disclosed for administering a medicament to a patient. In one aspect, a system includes an injection pen device in wireless communication with a mobile communication device. The injection pen device includes a housing including a chamber to encase a cartridge containing medicine, a dose setting and dispensing mechanism to set the mechanism to dispense a particular dose of the medicine from the loaded cartridge, a sensor unit to detect a dispensed dose based on positions and/or movements of the dose setting and dispensing mechanism, and an electronics unit in communication with the sensor unit to process the detected dispensed dose and time data associated with a dispensing event and to wirelessly transmit the dose data to a user's device. The mobile communication device provides a software application to provide the user with health information using the processed dose data.

Medicine administering system including injection pen and companion device

Systems, devices, and techniques are disclosed for administering and tracking medicine to patients and providing health management capabilities for patients and caregivers. In some aspects, a method includes receiving one or more analyte values associated with a health condition of the patient user; receiving contextual data associated with the patient user obtained by the mobile computing device, where the obtained contextual data includes information associated with a meal; determining a medicine metric value associated with an amount of medicine active in the body of the patient user; autonomously calculating a dose of the medicine without input from the user based at least on the one or more analyte values, the medicine metric value, and the information associated with a meal; and continuously displaying the calculated dose of the medicine.

Intelligent medication delivery systems and methods for dose recommendation and management

The present invention relates generally to systems and methods for processing, transmitting, and displaying data received from continuous analyte sensor, such as a glucose sensor. In some embodiments, the continuous analyte sensor system comprises a sensor electronics module that includes power saving features. One feature includes a low power measurement circuit that can be switched between a measurement mode and a low power mode, in which charging circuitry continues to apply power to electrodes of a sensor during the low power mode. In addition, the sensor electronics module can be switched between in a low power storage mode higher power operational mode via a switch. The switch can include a reed switch or optical switch, for example. A validation routine can also be implemented to ensure an interrupt signal sent from the switch is valid. The continuous analyte sensor can be physically connected to a sensor electronics module, which is in direct wireless communication with a plurality of different display devices.

Advanced continuous analyte monitoring system

Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor systemcomprising two working electrodes and at least one reference/counter electrode is provided. The sensor systemcomprises first and second elongated bodies E, E, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layerthat separates the conductive layerfrom the elongated body, a membrane layer deposited on top of the elongated bodies E, E, and working electrodes″ formed by removing portions of the conductive layerand the insulating layer, thereby exposing electroactive surface of the elongated bodies E, E

Analyte sensors and methods of manufacturing same

Systems, devices, and techniques are disclosed for administering and tracking medicine to patients and providing health management capabilities for patients and caregivers. In some aspects, a system includes an injection pen device including a dose setting mechanism, a dispensing mechanism, and an electronics unit to generate dose data associated with a dispensing event of a dose of the medicine dispensed from the injection pen device and time data associated with the dispensing event; a mobile device in wireless communication to receive and process the dose data; and a software application configured to determine a recommended dose based on health data and contextual data associated with a user of the injection pen device, the software application including a learning dose calculator module to adaptively calculate the recommended dose of the medicine based on time-relevant and circumstances-relevant data specific to the user of the injection pen device.

Intelligent medication delivery systems and methods

The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Transcutaneous analyte sensor

Intelligent (smart) tracking accessories for a medicine dispensing device, such as an injection pen or pen device, are described. A smart tracking accessory in the form of a smart cap for a medicine dispensing device, such as an insulin pen, is configured to protect the needle of the dispensing device and the medicine contained therein when the device is not in use. The smart cap may detect the presence of the medicine dispensing device, detect an activation event such as removal from the medicine dispensing device, inform the user whether it is safe to administer a therapeutic dose of medicine, and log occurrence of the dosing event.

Intelligent accessories for medicine dispensing device

Disclosed herein are techniques related to safeguards against separation from portable medicine delivery devices. In some embodiments, the techniques may involve monitoring a wireless connection established between a portable computing device and a portable medicine delivery device. The techniques may also involve making a determination, based on the result of the monitoring, that the portable medicine delivery device is outside a predetermined range of the portable computing device. The techniques may further involve generating a notification based on the determination. The notification may be indicative of a user of the portable computing device being unaccompanied by the portable medicine delivery device.

Safeguards against separation from portable medicine delivery devices

Systems and methods for compensating for effects of temperature on implantable sensors are provided. In some embodiments, systems and methods are provided for measuring a temperature to determine a change in temperature in a sensor environment. In certain embodiments, a temperature compensation factor is determined based on a change in temperature of the sensor environment. The temperature compensation factor can be used in processing raw data of an analyte signal to report a more accurate analyte concentration.

Devices, systems, and methods to compensate for effects of temperature on implantable sensors

Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.

System and methods for processing analyte sensor data for sensor calibration

Systems, devices, and techniques are disclosed for administering and tracking medicine to patients and providing health management capabilities for patients and caregivers. In some aspects, an intelligent medicine administering system includes a medicine injection device having a multi-channel encoder that detects fault conditions (e.g., such as open or short circuits) and a patient user's companion device including a software application operable to implement algorithms for detecting faults and communication loss and alerting the patient user for safety and fail-safes of the medicine injection device.

Intelligent medication delivery systems and methods for dose setting and dispensing monitoring

Growing community of inventors

Ladera Ranch, CA, United States of America

Jack Pryor